An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility

Nucleosome turnover concomitant with incorporation of the histone variant H3.3 is a hallmark of regulatory regions in the animal genome. Here, the authors demonstrate that fast histone turnover and H3.3 incorporation defines a dynamic heterochromatin state in pluripotent stem cells.

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Autores principales:	Carmen Navarro, Jing Lyu, Anna-Maria Katsori, Rozina Caridha, Simon J. Elsässer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0935d9b38bff4e838fc9ea0b408a07b4
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spelling	oai:doaj.org-article:0935d9b38bff4e838fc9ea0b408a07b42021-12-02T16:57:09ZAn embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility10.1038/s41467-020-18863-12041-1723https://doaj.org/article/0935d9b38bff4e838fc9ea0b408a07b42020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18863-1https://doaj.org/toc/2041-1723Nucleosome turnover concomitant with incorporation of the histone variant H3.3 is a hallmark of regulatory regions in the animal genome. Here, the authors demonstrate that fast histone turnover and H3.3 incorporation defines a dynamic heterochromatin state in pluripotent stem cells.Carmen NavarroJing LyuAnna-Maria KatsoriRozina CaridhaSimon J. ElsässerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carmen Navarro Jing Lyu Anna-Maria Katsori Rozina Caridha Simon J. Elsässer An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility
description	Nucleosome turnover concomitant with incorporation of the histone variant H3.3 is a hallmark of regulatory regions in the animal genome. Here, the authors demonstrate that fast histone turnover and H3.3 incorporation defines a dynamic heterochromatin state in pluripotent stem cells.
format	article
author	Carmen Navarro Jing Lyu Anna-Maria Katsori Rozina Caridha Simon J. Elsässer
author_facet	Carmen Navarro Jing Lyu Anna-Maria Katsori Rozina Caridha Simon J. Elsässer
author_sort	Carmen Navarro
title	An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility
title_short	An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility
title_full	An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility
title_fullStr	An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility
title_full_unstemmed	An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility
title_sort	embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of dna accessibility
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0935d9b38bff4e838fc9ea0b408a07b4
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An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility

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