Decreased expression of the thyroid hormone-inactivating enzyme type 3 deiodinase is associated with lower survival rates in breast cancer

Abstract Thyroid hormones (THs) are critical regulators of cellular processes, while changes in their levels impact all the hallmarks of cancer. Disturbed expression of type 3 deiodinase (DIO3), the main TH-inactivating enzyme, occurs in several human neoplasms and has been associated with adverse o...

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Autores principales: Iuri Martin Goemann, Vicente Rodrigues Marczyk, Mariana Recamonde-Mendoza, Simone Magagnin Wajner, Marcia Silveira Graudenz, Ana Luiza Maia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/09384b35a5ac4e0b98acda13cdac1ea7
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