A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial

Introduction: The establishment of good efficacy and safety of non-invasive methods in comparison with conventional methods would be the result of a higher ability for decision-making about the best therapeutic approach in patients with large ureteral calculi. Accordingly, this study was carried out...

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Autores principales:	Seyed Mohammad Kazem Aghamir, Mohammad Hatef Khorrami, Mohammad Saatchi, Hamidreza Zia, Seyed Naser Seyedesmaeili
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2020
Materias:	ureteral stone management minimally invasive surgery Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/093d1b34b60440c885e78efcef0dc390
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spelling	oai:doaj.org-article:093d1b34b60440c885e78efcef0dc3902021-11-30T05:30:22ZA Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial10.22034/TRU.2020.257000.10442717-042Xhttps://doaj.org/article/093d1b34b60440c885e78efcef0dc3902020-11-01T00:00:00Zhttps://www.transresurology.com/article_120016.htmlhttps://doaj.org/toc/2717-042XIntroduction: The establishment of good efficacy and safety of non-invasive methods in comparison with conventional methods would be the result of a higher ability for decision-making about the best therapeutic approach in patients with large ureteral calculi. Accordingly, this study was carried out to compare the efficacy of minimally invasive surgical ureterolithotomy (MISU) versus Transurethral Lithotripsy (TUL) plus Retrograde Intrarenal Surgery (RIRS) in patients with ureteral stones larger than 15 mm. Methods: In this single-blind randomized clinical trial, 74 consecutive patients with ureteral stones larger than 15 mm attending to Urology Clinic, Sina Hospital, and Tehran, Iran in 2017 were enrolled. Patients were randomly assigned to undergo minimally invasive surgical ureterolithotomy or TUL plus RIRS. Then the cases with remained stones over 2 mm after treatment were recognized by imaging and stone-free rate (SFR) was determined and compared across the groups. Results: Longer hospital stay, larger Apotel Infusion dose, and longer operation time were seen in the MISU group (P-value ≤ 0.00). The stone-free rate was 94.6% and 97.3% in TUL plus RIRS and MISU groups, respectively (P-value = 1.00). The rates of adverse effects were alike across the groups (P-value = 0.95) with considering fever that was higher in TUL plus RIRS group. Conclusions: Laparoscopic ureterolithotomy is an effective and safe surgical procedure for minimally invasive strategy when first-line therapeutic approaches were unsuccessful in patients with larger ureteral stones.Seyed Mohammad Kazem AghamirMohammad Hatef Khorrami Mohammad Saatchi Hamidreza ZiaSeyed Naser Seyedesmaeili Urology Research Centerarticleureteral stonemanagementminimally invasive surgeryDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 2, Iss 4, Pp 127-131 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	ureteral stone management minimally invasive surgery Diseases of the genitourinary system. Urology RC870-923
spellingShingle	ureteral stone management minimally invasive surgery Diseases of the genitourinary system. Urology RC870-923 Seyed Mohammad Kazem Aghamir Mohammad Hatef Khorrami Mohammad Saatchi Hamidreza Zia Seyed Naser Seyedesmaeili A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial
description	Introduction: The establishment of good efficacy and safety of non-invasive methods in comparison with conventional methods would be the result of a higher ability for decision-making about the best therapeutic approach in patients with large ureteral calculi. Accordingly, this study was carried out to compare the efficacy of minimally invasive surgical ureterolithotomy (MISU) versus Transurethral Lithotripsy (TUL) plus Retrograde Intrarenal Surgery (RIRS) in patients with ureteral stones larger than 15 mm. Methods: In this single-blind randomized clinical trial, 74 consecutive patients with ureteral stones larger than 15 mm attending to Urology Clinic, Sina Hospital, and Tehran, Iran in 2017 were enrolled. Patients were randomly assigned to undergo minimally invasive surgical ureterolithotomy or TUL plus RIRS. Then the cases with remained stones over 2 mm after treatment were recognized by imaging and stone-free rate (SFR) was determined and compared across the groups. Results: Longer hospital stay, larger Apotel Infusion dose, and longer operation time were seen in the MISU group (P-value ≤ 0.00). The stone-free rate was 94.6% and 97.3% in TUL plus RIRS and MISU groups, respectively (P-value = 1.00). The rates of adverse effects were alike across the groups (P-value = 0.95) with considering fever that was higher in TUL plus RIRS group. Conclusions: Laparoscopic ureterolithotomy is an effective and safe surgical procedure for minimally invasive strategy when first-line therapeutic approaches were unsuccessful in patients with larger ureteral stones.
format	article
author	Seyed Mohammad Kazem Aghamir Mohammad Hatef Khorrami Mohammad Saatchi Hamidreza Zia Seyed Naser Seyedesmaeili
author_facet	Seyed Mohammad Kazem Aghamir Mohammad Hatef Khorrami Mohammad Saatchi Hamidreza Zia Seyed Naser Seyedesmaeili
author_sort	Seyed Mohammad Kazem Aghamir
title	A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial
title_short	A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial
title_full	A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial
title_fullStr	A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial
title_full_unstemmed	A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial
title_sort	comparison of minimally invasive surgery ureterolithotomy and transurethral lithotripsy in combination with retrograde intrarenal surgery: a randomized clinical trial
publisher	Urology Research Center
publishDate	2020
url	https://doaj.org/article/093d1b34b60440c885e78efcef0dc390
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A Comparison of Minimally Invasive Surgery Ureterolithotomy and Transurethral Lithotripsy in Combination with Retrograde Intrarenal Surgery: A Randomized Clinical Trial

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