Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes

In genome-wide association studies, variant-level associations are hard to identify and can be difficult to interpret biologically. Here, the authors develop a new model-based enrichment analysis method, and apply it to identify new associated genes, pathways and tissues across 31 human phenotypes.

Guardado en:
Detalles Bibliográficos
Autores principales: Xiang Zhu, Matthew Stephens
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/09415081d3744dba8f88983498596104
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!