Prenylcysteine oxidase 1, an emerging player in atherosclerosis

Prenylcysteine oxidase 1, an emerging player in atherosclerosis

Banfi et al. investigate the role of Prenylcysteine oxidase 1 (PCYOX1), an enzyme implicated in catabolism of prenylated cysteine, in human and murine atherosclerosis. They find that loss of PCYOX1 is anti-atherogenic and understanding its biology and functions can potentially provide significant th...

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Autores principales: C. Banfi, R. Baetta, S. S. Barbieri, M. Brioschi, A. Guarino, S. Ghilardi, L. Sandrini, S. Eligini, G. Polvani, O. Bergman, P. Eriksson, E. Tremoli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/094301d561fb4a1493a780a94c656a05
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spelling oai:doaj.org-article:094301d561fb4a1493a780a94c656a052021-12-02T18:48:42ZPrenylcysteine oxidase 1, an emerging player in atherosclerosis10.1038/s42003-021-02630-z2399-3642https://doaj.org/article/094301d561fb4a1493a780a94c656a052021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02630-zhttps://doaj.org/toc/2399-3642Banfi et al. investigate the role of Prenylcysteine oxidase 1 (PCYOX1), an enzyme implicated in catabolism of prenylated cysteine, in human and murine atherosclerosis. They find that loss of PCYOX1 is anti-atherogenic and understanding its biology and functions can potentially provide significant therapeutic opportunities in addressing atherosclerosis.C. BanfiR. BaettaS. S. BarbieriM. BrioschiA. GuarinoS. GhilardiL. SandriniS. EliginiG. PolvaniO. BergmanP. ErikssonE. TremoliNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
C. Banfi
R. Baetta
S. S. Barbieri
M. Brioschi
A. Guarino
S. Ghilardi
L. Sandrini
S. Eligini
G. Polvani
O. Bergman
P. Eriksson
E. Tremoli
Prenylcysteine oxidase 1, an emerging player in atherosclerosis
description Banfi et al. investigate the role of Prenylcysteine oxidase 1 (PCYOX1), an enzyme implicated in catabolism of prenylated cysteine, in human and murine atherosclerosis. They find that loss of PCYOX1 is anti-atherogenic and understanding its biology and functions can potentially provide significant therapeutic opportunities in addressing atherosclerosis.
format article
author C. Banfi
R. Baetta
S. S. Barbieri
M. Brioschi
A. Guarino
S. Ghilardi
L. Sandrini
S. Eligini
G. Polvani
O. Bergman
P. Eriksson
E. Tremoli
author_facet C. Banfi
R. Baetta
S. S. Barbieri
M. Brioschi
A. Guarino
S. Ghilardi
L. Sandrini
S. Eligini
G. Polvani
O. Bergman
P. Eriksson
E. Tremoli
author_sort C. Banfi
title Prenylcysteine oxidase 1, an emerging player in atherosclerosis
title_short Prenylcysteine oxidase 1, an emerging player in atherosclerosis
title_full Prenylcysteine oxidase 1, an emerging player in atherosclerosis
title_fullStr Prenylcysteine oxidase 1, an emerging player in atherosclerosis
title_full_unstemmed Prenylcysteine oxidase 1, an emerging player in atherosclerosis
title_sort prenylcysteine oxidase 1, an emerging player in atherosclerosis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/094301d561fb4a1493a780a94c656a05
work_keys_str_mv AT cbanfi prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT rbaetta prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT ssbarbieri prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT mbrioschi prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT aguarino prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT sghilardi prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT lsandrini prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT seligini prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT gpolvani prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT obergman prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT periksson prenylcysteineoxidase1anemergingplayerinatherosclerosis
AT etremoli prenylcysteineoxidase1anemergingplayerinatherosclerosis
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