Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

Abstract Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery...

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Autores principales: Giovanni Savarino, Maurizio Carta, Marcello Cimador, Antonio Corsello, Mario Giuffrè, Ingrid Anne Mandy Schierz, Gregorio Serra, Giovanni Corsello
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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NEC
Acceso en línea:https://doaj.org/article/09460f40ce864090930b1be8f6a55520
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Sumario:Abstract Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.