Reconstructing metastatic seeding patterns of human cancers

Tumours frequently metastasize to multiple anatomical sites and understanding how these different metastases evolve may be important for therapy. Here, the authors develop a method—Treeomics—that can construct phylogenies from multiple metastases from next-generation sequencing data.

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Autores principales:	Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Ivana Bozic, Krishnendu Chatterjee, Christine A. Iacobuzio-Donahue, Bert Vogelstein, Martin A. Nowak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/094af776195f4129b91a819f0e100749
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spelling	oai:doaj.org-article:094af776195f4129b91a819f0e1007492021-12-02T15:38:45ZReconstructing metastatic seeding patterns of human cancers10.1038/ncomms141142041-1723https://doaj.org/article/094af776195f4129b91a819f0e1007492017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14114https://doaj.org/toc/2041-1723Tumours frequently metastasize to multiple anatomical sites and understanding how these different metastases evolve may be important for therapy. Here, the authors develop a method—Treeomics—that can construct phylogenies from multiple metastases from next-generation sequencing data.Johannes G. ReiterAlvin P. Makohon-MooreJeffrey M. GeroldIvana BozicKrishnendu ChatterjeeChristine A. Iacobuzio-DonahueBert VogelsteinMartin A. NowakNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johannes G. Reiter Alvin P. Makohon-Moore Jeffrey M. Gerold Ivana Bozic Krishnendu Chatterjee Christine A. Iacobuzio-Donahue Bert Vogelstein Martin A. Nowak Reconstructing metastatic seeding patterns of human cancers
description	Tumours frequently metastasize to multiple anatomical sites and understanding how these different metastases evolve may be important for therapy. Here, the authors develop a method—Treeomics—that can construct phylogenies from multiple metastases from next-generation sequencing data.
format	article
author	Johannes G. Reiter Alvin P. Makohon-Moore Jeffrey M. Gerold Ivana Bozic Krishnendu Chatterjee Christine A. Iacobuzio-Donahue Bert Vogelstein Martin A. Nowak
author_facet	Johannes G. Reiter Alvin P. Makohon-Moore Jeffrey M. Gerold Ivana Bozic Krishnendu Chatterjee Christine A. Iacobuzio-Donahue Bert Vogelstein Martin A. Nowak
author_sort	Johannes G. Reiter
title	Reconstructing metastatic seeding patterns of human cancers
title_short	Reconstructing metastatic seeding patterns of human cancers
title_full	Reconstructing metastatic seeding patterns of human cancers
title_fullStr	Reconstructing metastatic seeding patterns of human cancers
title_full_unstemmed	Reconstructing metastatic seeding patterns of human cancers
title_sort	reconstructing metastatic seeding patterns of human cancers
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/094af776195f4129b91a819f0e100749
work_keys_str_mv	AT johannesgreiter reconstructingmetastaticseedingpatternsofhumancancers AT alvinpmakohonmoore reconstructingmetastaticseedingpatternsofhumancancers AT jeffreymgerold reconstructingmetastaticseedingpatternsofhumancancers AT ivanabozic reconstructingmetastaticseedingpatternsofhumancancers AT krishnenduchatterjee reconstructingmetastaticseedingpatternsofhumancancers AT christineaiacobuziodonahue reconstructingmetastaticseedingpatternsofhumancancers AT bertvogelstein reconstructingmetastaticseedingpatternsofhumancancers AT martinanowak reconstructingmetastaticseedingpatternsofhumancancers
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Reconstructing metastatic seeding patterns of human cancers

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