Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour
Drug addiction is partially heritable but the non-genetic inheritance mechanisms are not well understood. The authors show that motivation of male rats in response to cocaine self-administration elicit susceptibility and/or decreased resistance to developing addiction like behaviour in offspring.
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Nature Portfolio
2017
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oai:doaj.org-article:094c1b7ec7124386ad183697cf2ffd002021-12-02T14:42:18ZDrug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour10.1038/ncomms155272041-1723https://doaj.org/article/094c1b7ec7124386ad183697cf2ffd002017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15527https://doaj.org/toc/2041-1723Drug addiction is partially heritable but the non-genetic inheritance mechanisms are not well understood. The authors show that motivation of male rats in response to cocaine self-administration elicit susceptibility and/or decreased resistance to developing addiction like behaviour in offspring.Qiumin LeBiao YanXiangchen YuYanqing LiHaikun SongHuiwen ZhuWeiqing HouDingailu MaFeizhen WuYuqing ZhouLan MaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Qiumin Le Biao Yan Xiangchen Yu Yanqing Li Haikun Song Huiwen Zhu Weiqing Hou Dingailu Ma Feizhen Wu Yuqing Zhou Lan Ma Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour |
description |
Drug addiction is partially heritable but the non-genetic inheritance mechanisms are not well understood. The authors show that motivation of male rats in response to cocaine self-administration elicit susceptibility and/or decreased resistance to developing addiction like behaviour in offspring. |
format |
article |
author |
Qiumin Le Biao Yan Xiangchen Yu Yanqing Li Haikun Song Huiwen Zhu Weiqing Hou Dingailu Ma Feizhen Wu Yuqing Zhou Lan Ma |
author_facet |
Qiumin Le Biao Yan Xiangchen Yu Yanqing Li Haikun Song Huiwen Zhu Weiqing Hou Dingailu Ma Feizhen Wu Yuqing Zhou Lan Ma |
author_sort |
Qiumin Le |
title |
Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour |
title_short |
Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour |
title_full |
Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour |
title_fullStr |
Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour |
title_full_unstemmed |
Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour |
title_sort |
drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/094c1b7ec7124386ad183697cf2ffd00 |
work_keys_str_mv |
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