Sirtuin Lipoamidase Activity Is Conserved in Bacteria as a Regulator of Metabolic Enzyme Complexes

ABSTRACT Lipoic acid is an essential metabolic cofactor added as a posttranslational modification on several multimeric enzyme complexes. These protein complexes, evolutionarily conserved from bacteria to humans, are core regulators of cellular metabolism. While the multistep enzymatic process of ad...

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Auteurs principaux: Elizabeth A. Rowland, Todd M. Greco, Caroline K. Snowden, Anne L. McCabe, Thomas J. Silhavy, Ileana M. Cristea
Format: article
Langue:EN
Publié: American Society for Microbiology 2017
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Accès en ligne:https://doaj.org/article/094c79d00ce743b08776e6a6ed57377e
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