Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability.

The inflammasome has been recently implicated in obesity-associated dys-metabolism. However, of its products, the specific role of IL-1β was clinically demonstrated to mediate only the pancreatic beta-cell demise, and in mice mainly the intra-hepatic manifestations of obesity. Yet, it remains largel...

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Autores principales: Ori Nov, Hagit Shapiro, Hilla Ovadia, Tanya Tarnovscki, Irit Dvir, Elad Shemesh, Julia Kovsan, Ilan Shelef, Yaron Carmi, Elena Voronov, Ron N Apte, Eli Lewis, Yulia Haim, Daniel Konrad, Nava Bashan, Assaf Rudich
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/09511dcc0e7c4946be115d467ef91db4
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