Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability.
The inflammasome has been recently implicated in obesity-associated dys-metabolism. However, of its products, the specific role of IL-1β was clinically demonstrated to mediate only the pancreatic beta-cell demise, and in mice mainly the intra-hepatic manifestations of obesity. Yet, it remains largel...
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Autores principales: | Ori Nov, Hagit Shapiro, Hilla Ovadia, Tanya Tarnovscki, Irit Dvir, Elad Shemesh, Julia Kovsan, Ilan Shelef, Yaron Carmi, Elena Voronov, Ron N Apte, Eli Lewis, Yulia Haim, Daniel Konrad, Nava Bashan, Assaf Rudich |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/09511dcc0e7c4946be115d467ef91db4 |
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