A Novel Type of PD-L1 Inhibitor rU1 snRNPA From Human-Derived Protein Scaffolds Library
Three marketed anti-PD-L1 antibodies almost have severe immune-mediated side effects. The therapeutic effects of anti-PD-L1 chemical inhibitors are not satisfied in the clinical trials. Here we constructed human-derived protein scaffolds library and screened scaffolds with a shape complementary to t...
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Auteurs principaux: | Chuang Ma, Sennan Qiao, Zhiyi Liu, Liang Shan, Chongyang Liang, Meiling Fan, Fei Sun |
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Format: | article |
Langue: | EN |
Publié: |
Frontiers Media S.A.
2021
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Accès en ligne: | https://doaj.org/article/09525b623e454bf2bbae4966a3b7676f |
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