High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs

How genetic adaptation and phenotypic acclimation are interrelated and allow Pseudomonas aeruginosa to persist in cystic fibrosis lungs is poorly understood. Here, Rossi et al. use high-resolution transcriptomics on expectorates to link phenotypic conservation to ecological flexibility and persisten...

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Autores principales: Elio Rossi, Marilena Falcone, Søren Molin, Helle Krogh Johansen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0959552299764ca3a149a66035cdef10
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spelling oai:doaj.org-article:0959552299764ca3a149a66035cdef102021-12-02T17:31:30ZHigh-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs10.1038/s41467-018-05944-52041-1723https://doaj.org/article/0959552299764ca3a149a66035cdef102018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05944-5https://doaj.org/toc/2041-1723How genetic adaptation and phenotypic acclimation are interrelated and allow Pseudomonas aeruginosa to persist in cystic fibrosis lungs is poorly understood. Here, Rossi et al. use high-resolution transcriptomics on expectorates to link phenotypic conservation to ecological flexibility and persistence.Elio RossiMarilena FalconeSøren MolinHelle Krogh JohansenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Elio Rossi
Marilena Falcone
Søren Molin
Helle Krogh Johansen
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
description How genetic adaptation and phenotypic acclimation are interrelated and allow Pseudomonas aeruginosa to persist in cystic fibrosis lungs is poorly understood. Here, Rossi et al. use high-resolution transcriptomics on expectorates to link phenotypic conservation to ecological flexibility and persistence.
format article
author Elio Rossi
Marilena Falcone
Søren Molin
Helle Krogh Johansen
author_facet Elio Rossi
Marilena Falcone
Søren Molin
Helle Krogh Johansen
author_sort Elio Rossi
title High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
title_short High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
title_full High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
title_fullStr High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
title_full_unstemmed High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
title_sort high-resolution in situ transcriptomics of pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0959552299764ca3a149a66035cdef10
work_keys_str_mv AT eliorossi highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs
AT marilenafalcone highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs
AT sørenmolin highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs
AT hellekroghjohansen highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs
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