High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
How genetic adaptation and phenotypic acclimation are interrelated and allow Pseudomonas aeruginosa to persist in cystic fibrosis lungs is poorly understood. Here, Rossi et al. use high-resolution transcriptomics on expectorates to link phenotypic conservation to ecological flexibility and persisten...
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2018
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oai:doaj.org-article:0959552299764ca3a149a66035cdef102021-12-02T17:31:30ZHigh-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs10.1038/s41467-018-05944-52041-1723https://doaj.org/article/0959552299764ca3a149a66035cdef102018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05944-5https://doaj.org/toc/2041-1723How genetic adaptation and phenotypic acclimation are interrelated and allow Pseudomonas aeruginosa to persist in cystic fibrosis lungs is poorly understood. Here, Rossi et al. use high-resolution transcriptomics on expectorates to link phenotypic conservation to ecological flexibility and persistence.Elio RossiMarilena FalconeSøren MolinHelle Krogh JohansenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
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Science Q Elio Rossi Marilena Falcone Søren Molin Helle Krogh Johansen High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs |
description |
How genetic adaptation and phenotypic acclimation are interrelated and allow Pseudomonas aeruginosa to persist in cystic fibrosis lungs is poorly understood. Here, Rossi et al. use high-resolution transcriptomics on expectorates to link phenotypic conservation to ecological flexibility and persistence. |
format |
article |
author |
Elio Rossi Marilena Falcone Søren Molin Helle Krogh Johansen |
author_facet |
Elio Rossi Marilena Falcone Søren Molin Helle Krogh Johansen |
author_sort |
Elio Rossi |
title |
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs |
title_short |
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs |
title_full |
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs |
title_fullStr |
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs |
title_full_unstemmed |
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs |
title_sort |
high-resolution in situ transcriptomics of pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/0959552299764ca3a149a66035cdef10 |
work_keys_str_mv |
AT eliorossi highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs AT marilenafalcone highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs AT sørenmolin highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs AT hellekroghjohansen highresolutioninsitutranscriptomicsofpseudomonasaeruginosaunveilsgenotypeindependentpathophenotypesincysticfibrosislungs |
_version_ |
1718380594009735168 |