Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants.

Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants.

Celiac disease (CD) is a unique autoimmune disorder in which the genetic factors (DQ2/DQ8) and the environmental trigger (gluten) are known and necessary but not sufficient for its development. Other environmental components contributing to CD are poorly understood. Studies suggest that aspects of g...

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Main Authors: Maria Sellitto, Guoyun Bai, Gloria Serena, W Florian Fricke, Craig Sturgeon, Pawel Gajer, James R White, Sara S K Koenig, Joyce Sakamoto, Dustin Boothe, Rachel Gicquelais, Deborah Kryszak, Elaine Puppa, Carlo Catassi, Jacques Ravel, Alessio Fasano
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/095af8d052d04096b09b4a1fb8a76b78
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