RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family

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RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family

Osteoarthritis is characterised by degeneration of joint cartilage. Here the authors show that the RNA-binding protein ZFP36L1 is upregulated in chondrocytes of humans and mice with osteoarthritis, and that its knockdown in mouse joints protects chondrocytes against apoptosis by modulating the funct...

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Auteurs principaux:	Young-Ok Son, Hyo-Eun Kim, Wan-Su Choi, Churl-Hong Chun, Jang-Soo Chun
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/095fcf13e8894eaf918d58885ed8bdac
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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