Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly

Vesicle associated membrane protein 2 (VAMP2) contains a conserved SNARE motif that interacts with syntaxin-1 and SNAP25 for SNARE complex assembly. Here authors use in-cell NMR spectroscopy to describe the dynamic membrane association of VAMP2 SNARE motif in mammalian cells at the atomic resolution...

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Autores principales:	Chuchu Wang, Jia Tu, Shengnan Zhang, Bin Cai, Zhenying Liu, Shouqiao Hou, Qinglu Zhong, Xiao Hu, Wenbin Liu, Guohui Li, Zhijun Liu, Lin He, Jiajie Diao, Zheng-Jiang Zhu, Dan Li, Cong Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0967f87a5aae4500b37410d2f85f412c
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spelling	oai:doaj.org-article:0967f87a5aae4500b37410d2f85f412c2021-12-02T14:42:15ZDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly10.1038/s41467-020-15270-42041-1723https://doaj.org/article/0967f87a5aae4500b37410d2f85f412c2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15270-4https://doaj.org/toc/2041-1723Vesicle associated membrane protein 2 (VAMP2) contains a conserved SNARE motif that interacts with syntaxin-1 and SNAP25 for SNARE complex assembly. Here authors use in-cell NMR spectroscopy to describe the dynamic membrane association of VAMP2 SNARE motif in mammalian cells at the atomic resolution.Chuchu WangJia TuShengnan ZhangBin CaiZhenying LiuShouqiao HouQinglu ZhongXiao HuWenbin LiuGuohui LiZhijun LiuLin HeJiajie DiaoZheng-Jiang ZhuDan LiCong LiuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chuchu Wang Jia Tu Shengnan Zhang Bin Cai Zhenying Liu Shouqiao Hou Qinglu Zhong Xiao Hu Wenbin Liu Guohui Li Zhijun Liu Lin He Jiajie Diao Zheng-Jiang Zhu Dan Li Cong Liu Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
description	Vesicle associated membrane protein 2 (VAMP2) contains a conserved SNARE motif that interacts with syntaxin-1 and SNAP25 for SNARE complex assembly. Here authors use in-cell NMR spectroscopy to describe the dynamic membrane association of VAMP2 SNARE motif in mammalian cells at the atomic resolution.
format	article
author	Chuchu Wang Jia Tu Shengnan Zhang Bin Cai Zhenying Liu Shouqiao Hou Qinglu Zhong Xiao Hu Wenbin Liu Guohui Li Zhijun Liu Lin He Jiajie Diao Zheng-Jiang Zhu Dan Li Cong Liu
author_facet	Chuchu Wang Jia Tu Shengnan Zhang Bin Cai Zhenying Liu Shouqiao Hou Qinglu Zhong Xiao Hu Wenbin Liu Guohui Li Zhijun Liu Lin He Jiajie Diao Zheng-Jiang Zhu Dan Li Cong Liu
author_sort	Chuchu Wang
title	Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
title_short	Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
title_full	Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
title_fullStr	Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
title_full_unstemmed	Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
title_sort	different regions of synaptic vesicle membrane regulate vamp2 conformation for the snare assembly
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0967f87a5aae4500b37410d2f85f412c
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_version_	1718389731518054400

Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly

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