Emerging functions for the Staphylococcus aureus RNome.

Staphylococcus aureus is a leading pathogen for animals and humans, not only being one of the most frequently isolated bacteria in hospital-associated infections but also causing diseases in the community. To coordinate the expression of its numerous virulence genes for growth and survival, S. aureu...

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Autores principales:	Julien Guillet, Marc Hallier, Brice Felden
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/0975b7b879ca4eaa9a6195e38ec5f5be
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spelling	oai:doaj.org-article:0975b7b879ca4eaa9a6195e38ec5f5be2021-11-18T06:07:15ZEmerging functions for the Staphylococcus aureus RNome.1553-73661553-737410.1371/journal.ppat.1003767https://doaj.org/article/0975b7b879ca4eaa9a6195e38ec5f5be2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24348246/pdf/?tool=EBIhttps://doaj.org/toc/1553-7366https://doaj.org/toc/1553-7374Staphylococcus aureus is a leading pathogen for animals and humans, not only being one of the most frequently isolated bacteria in hospital-associated infections but also causing diseases in the community. To coordinate the expression of its numerous virulence genes for growth and survival, S. aureus uses various signalling pathways that include two-component regulatory systems, transcription factors, and also around 250 regulatory RNAs. Biological roles have only been determined for a handful of these sRNAs, including cis, trans, and cis-trans acting RNAs, some internally encoding small, functional peptides and others possessing dual or multiple functions. Here we put forward an inventory of these fascinating sRNAs; the proteins involved in their activities; and those involved in stress response, metabolisms, and virulence.Julien GuilletMarc HallierBrice FeldenPublic Library of Science (PLoS)articleImmunologic diseases. AllergyRC581-607Biology (General)QH301-705.5ENPLoS Pathogens, Vol 9, Iss 12, p e1003767 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
spellingShingle	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5 Julien Guillet Marc Hallier Brice Felden Emerging functions for the Staphylococcus aureus RNome.
description	Staphylococcus aureus is a leading pathogen for animals and humans, not only being one of the most frequently isolated bacteria in hospital-associated infections but also causing diseases in the community. To coordinate the expression of its numerous virulence genes for growth and survival, S. aureus uses various signalling pathways that include two-component regulatory systems, transcription factors, and also around 250 regulatory RNAs. Biological roles have only been determined for a handful of these sRNAs, including cis, trans, and cis-trans acting RNAs, some internally encoding small, functional peptides and others possessing dual or multiple functions. Here we put forward an inventory of these fascinating sRNAs; the proteins involved in their activities; and those involved in stress response, metabolisms, and virulence.
format	article
author	Julien Guillet Marc Hallier Brice Felden
author_facet	Julien Guillet Marc Hallier Brice Felden
author_sort	Julien Guillet
title	Emerging functions for the Staphylococcus aureus RNome.
title_short	Emerging functions for the Staphylococcus aureus RNome.
title_full	Emerging functions for the Staphylococcus aureus RNome.
title_fullStr	Emerging functions for the Staphylococcus aureus RNome.
title_full_unstemmed	Emerging functions for the Staphylococcus aureus RNome.
title_sort	emerging functions for the staphylococcus aureus rnome.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/0975b7b879ca4eaa9a6195e38ec5f5be
work_keys_str_mv	AT julienguillet emergingfunctionsforthestaphylococcusaureusrnome AT marchallier emergingfunctionsforthestaphylococcusaureusrnome AT bricefelden emergingfunctionsforthestaphylococcusaureusrnome
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Emerging functions for the Staphylococcus aureus RNome.

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