Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus

In the context of increasing bacterial antibiotic-resistance, gene therapy that targets the immune system to clear infection is a major goal. Here the authors show a silicon based nanosystem that modulates the macrophage response in an in vivo model of Staphylococcal pneumonia.

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Autores principales:	Byungji Kim, Hong-Bo Pang, Jinyoung Kang, Ji-Ho Park, Erkki Ruoslahti, Michael J. Sailor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/098171d737834a66a71effee6e976c20
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spelling	oai:doaj.org-article:098171d737834a66a71effee6e976c202021-12-02T14:39:09ZImmunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus10.1038/s41467-018-04390-72041-1723https://doaj.org/article/098171d737834a66a71effee6e976c202018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04390-7https://doaj.org/toc/2041-1723In the context of increasing bacterial antibiotic-resistance, gene therapy that targets the immune system to clear infection is a major goal. Here the authors show a silicon based nanosystem that modulates the macrophage response in an in vivo model of Staphylococcal pneumonia.Byungji KimHong-Bo PangJinyoung KangJi-Ho ParkErkki RuoslahtiMichael J. SailorNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Byungji Kim Hong-Bo Pang Jinyoung Kang Ji-Ho Park Erkki Ruoslahti Michael J. Sailor Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus
description	In the context of increasing bacterial antibiotic-resistance, gene therapy that targets the immune system to clear infection is a major goal. Here the authors show a silicon based nanosystem that modulates the macrophage response in an in vivo model of Staphylococcal pneumonia.
format	article
author	Byungji Kim Hong-Bo Pang Jinyoung Kang Ji-Ho Park Erkki Ruoslahti Michael J. Sailor
author_facet	Byungji Kim Hong-Bo Pang Jinyoung Kang Ji-Ho Park Erkki Ruoslahti Michael J. Sailor
author_sort	Byungji Kim
title	Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus
title_short	Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus
title_full	Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus
title_fullStr	Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus
title_full_unstemmed	Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus
title_sort	immunogene therapy with fusogenic nanoparticles modulates macrophage response to staphylococcus aureus
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/098171d737834a66a71effee6e976c20
work_keys_str_mv	AT byungjikim immunogenetherapywithfusogenicnanoparticlesmodulatesmacrophageresponsetostaphylococcusaureus AT hongbopang immunogenetherapywithfusogenicnanoparticlesmodulatesmacrophageresponsetostaphylococcusaureus AT jinyoungkang immunogenetherapywithfusogenicnanoparticlesmodulatesmacrophageresponsetostaphylococcusaureus AT jihopark immunogenetherapywithfusogenicnanoparticlesmodulatesmacrophageresponsetostaphylococcusaureus AT erkkiruoslahti immunogenetherapywithfusogenicnanoparticlesmodulatesmacrophageresponsetostaphylococcusaureus AT michaeljsailor immunogenetherapywithfusogenicnanoparticlesmodulatesmacrophageresponsetostaphylococcusaureus
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Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus

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