Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus

In the context of increasing bacterial antibiotic-resistance, gene therapy that targets the immune system to clear infection is a major goal. Here the authors show a silicon based nanosystem that modulates the macrophage response in an in vivo model of Staphylococcal pneumonia.

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Bibliographic Details
Main Authors: Byungji Kim, Hong-Bo Pang, Jinyoung Kang, Ji-Ho Park, Erkki Ruoslahti, Michael J. Sailor
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/098171d737834a66a71effee6e976c20
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