Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.

<h4>Objectives</h4>To determine whether for a given waist circumference (WC), a larger hip circumference (HC) was associated with a reduced risk of insulin resistance, type 2 diabetes (T2D), hypertension and cardiovascular disease (CVD) in HIV-infected patients. A second objective was to...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Trevor O'Neill, Giovanni Guaraldi, Gabriella Orlando, Federica Carli, Elisa Garlassi, Stefano Zona, Jean-Pierre Després, Robert Ross
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
R
Q
Acceso en línea:https://doaj.org/article/098608a0e32f42d69a29aabee1bbe0a9
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:098608a0e32f42d69a29aabee1bbe0a9
record_format dspace
spelling oai:doaj.org-article:098608a0e32f42d69a29aabee1bbe0a92021-11-18T07:45:12ZCombined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.1932-620310.1371/journal.pone.0062538https://doaj.org/article/098608a0e32f42d69a29aabee1bbe0a92013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23700409/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objectives</h4>To determine whether for a given waist circumference (WC), a larger hip circumference (HC) was associated with a reduced risk of insulin resistance, type 2 diabetes (T2D), hypertension and cardiovascular disease (CVD) in HIV-infected patients. A second objective was to determine whether, for a given WC, the addition of HC improved upon estimates of abdominal adiposity, in particular visceral adipose tissue (VAT), compared to those obtained by WC alone.<h4>Methods</h4>HIV-infected men (N = 1481) and women (N = 841) were recruited between 2005 and 2009. WC and HC were obtained using standard techniques and abdominal adiposity was measured using computed tomography.<h4>Results</h4>After control for WC and covariates, HC was negatively associated with risk of insulin resistance (p<0.05) and T2D [Men: OR = 0.91 (95% CI: 0.86-0.96); Women: OR = 0.91 (95% CI: 0.84-0.98)]. For a given WC, HC was also negatively associated with a lower risk of hypertension (p<0.05) and CVD [OR = 0.94 (95% CI: 0.88-0.99)] in men, but not women. Although HC was negatively associated with VAT in men and women after control for WC (p<0.05), the addition of HC did not substantially improve upon the prediction of VAT compared to WC alone.<h4>Conclusions</h4>The identification of HIV-infected individuals at increased health risk by WC alone is substantially improved by the addition of HC. Estimates of visceral adipose tissue by WC are not substantially improved by the addition of HC and thus variation in visceral adiposity may not be the conduit by which HC identifies increased health risk.Trevor O'NeillGiovanni GuaraldiGabriella OrlandoFederica CarliElisa GarlassiStefano ZonaJean-Pierre DesprésRobert RossPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 5, p e62538 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Trevor O'Neill
Giovanni Guaraldi
Gabriella Orlando
Federica Carli
Elisa Garlassi
Stefano Zona
Jean-Pierre Després
Robert Ross
Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.
description <h4>Objectives</h4>To determine whether for a given waist circumference (WC), a larger hip circumference (HC) was associated with a reduced risk of insulin resistance, type 2 diabetes (T2D), hypertension and cardiovascular disease (CVD) in HIV-infected patients. A second objective was to determine whether, for a given WC, the addition of HC improved upon estimates of abdominal adiposity, in particular visceral adipose tissue (VAT), compared to those obtained by WC alone.<h4>Methods</h4>HIV-infected men (N = 1481) and women (N = 841) were recruited between 2005 and 2009. WC and HC were obtained using standard techniques and abdominal adiposity was measured using computed tomography.<h4>Results</h4>After control for WC and covariates, HC was negatively associated with risk of insulin resistance (p<0.05) and T2D [Men: OR = 0.91 (95% CI: 0.86-0.96); Women: OR = 0.91 (95% CI: 0.84-0.98)]. For a given WC, HC was also negatively associated with a lower risk of hypertension (p<0.05) and CVD [OR = 0.94 (95% CI: 0.88-0.99)] in men, but not women. Although HC was negatively associated with VAT in men and women after control for WC (p<0.05), the addition of HC did not substantially improve upon the prediction of VAT compared to WC alone.<h4>Conclusions</h4>The identification of HIV-infected individuals at increased health risk by WC alone is substantially improved by the addition of HC. Estimates of visceral adipose tissue by WC are not substantially improved by the addition of HC and thus variation in visceral adiposity may not be the conduit by which HC identifies increased health risk.
format article
author Trevor O'Neill
Giovanni Guaraldi
Gabriella Orlando
Federica Carli
Elisa Garlassi
Stefano Zona
Jean-Pierre Després
Robert Ross
author_facet Trevor O'Neill
Giovanni Guaraldi
Gabriella Orlando
Federica Carli
Elisa Garlassi
Stefano Zona
Jean-Pierre Després
Robert Ross
author_sort Trevor O'Neill
title Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.
title_short Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.
title_full Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.
title_fullStr Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.
title_full_unstemmed Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.
title_sort combined use of waist and hip circumference to identify abdominally obese hiv-infected patients at increased health risk.
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doaj.org/article/098608a0e32f42d69a29aabee1bbe0a9
work_keys_str_mv AT trevoroneill combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
AT giovanniguaraldi combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
AT gabriellaorlando combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
AT federicacarli combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
AT elisagarlassi combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
AT stefanozona combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
AT jeanpierredespres combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
AT robertross combineduseofwaistandhipcircumferencetoidentifyabdominallyobesehivinfectedpatientsatincreasedhealthrisk
_version_ 1718423014988578816