The shifting demographic landscape of pandemic influenza.

<h4>Background</h4>As Pandemic (H1N1) 2009 influenza spreads around the globe, it strikes school-age children more often than adults. Although there is some evidence of pre-existing immunity among older adults, this alone may not explain the significant gap in age-specific infection rate...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shweta Bansal, Babak Pourbohloul, Nathaniel Hupert, Bryan Grenfell, Lauren Ancel Meyers
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2010
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/09909e7df9c148f8ade753c24c8da68a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:09909e7df9c148f8ade753c24c8da68a
record_format	dspace
spelling	oai:doaj.org-article:09909e7df9c148f8ade753c24c8da68a2021-11-25T06:25:32ZThe shifting demographic landscape of pandemic influenza.1932-620310.1371/journal.pone.0009360https://doaj.org/article/09909e7df9c148f8ade753c24c8da68a2010-02-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20195468/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>As Pandemic (H1N1) 2009 influenza spreads around the globe, it strikes school-age children more often than adults. Although there is some evidence of pre-existing immunity among older adults, this alone may not explain the significant gap in age-specific infection rates.<h4>Methods and findings</h4>Based on a retrospective analysis of pandemic strains of influenza from the last century, we show that school-age children typically experience the highest attack rates in primarily naive populations, with the burden shifting to adults during the subsequent season. Using a parsimonious network-based mathematical model which incorporates the changing distribution of contacts in the susceptible population, we demonstrate that new pandemic strains of influenza are expected to shift the epidemiological landscape in exactly this way.<h4>Conclusions</h4>Our analysis provides a simple demographic explanation for the age bias observed for H1N1/09 attack rates, and suggests that this bias may shift in coming months. These results have significant implications for the allocation of public health resources for H1N1/09 and future influenza pandemics.Shweta BansalBabak PourbohloulNathaniel HupertBryan GrenfellLauren Ancel MeyersPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 5, Iss 2, p e9360 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shweta Bansal Babak Pourbohloul Nathaniel Hupert Bryan Grenfell Lauren Ancel Meyers The shifting demographic landscape of pandemic influenza.
description	<h4>Background</h4>As Pandemic (H1N1) 2009 influenza spreads around the globe, it strikes school-age children more often than adults. Although there is some evidence of pre-existing immunity among older adults, this alone may not explain the significant gap in age-specific infection rates.<h4>Methods and findings</h4>Based on a retrospective analysis of pandemic strains of influenza from the last century, we show that school-age children typically experience the highest attack rates in primarily naive populations, with the burden shifting to adults during the subsequent season. Using a parsimonious network-based mathematical model which incorporates the changing distribution of contacts in the susceptible population, we demonstrate that new pandemic strains of influenza are expected to shift the epidemiological landscape in exactly this way.<h4>Conclusions</h4>Our analysis provides a simple demographic explanation for the age bias observed for H1N1/09 attack rates, and suggests that this bias may shift in coming months. These results have significant implications for the allocation of public health resources for H1N1/09 and future influenza pandemics.
format	article
author	Shweta Bansal Babak Pourbohloul Nathaniel Hupert Bryan Grenfell Lauren Ancel Meyers
author_facet	Shweta Bansal Babak Pourbohloul Nathaniel Hupert Bryan Grenfell Lauren Ancel Meyers
author_sort	Shweta Bansal
title	The shifting demographic landscape of pandemic influenza.
title_short	The shifting demographic landscape of pandemic influenza.
title_full	The shifting demographic landscape of pandemic influenza.
title_fullStr	The shifting demographic landscape of pandemic influenza.
title_full_unstemmed	The shifting demographic landscape of pandemic influenza.
title_sort	shifting demographic landscape of pandemic influenza.
publisher	Public Library of Science (PLoS)
publishDate	2010
url	https://doaj.org/article/09909e7df9c148f8ade753c24c8da68a
work_keys_str_mv	AT shwetabansal theshiftingdemographiclandscapeofpandemicinfluenza AT babakpourbohloul theshiftingdemographiclandscapeofpandemicinfluenza AT nathanielhupert theshiftingdemographiclandscapeofpandemicinfluenza AT bryangrenfell theshiftingdemographiclandscapeofpandemicinfluenza AT laurenancelmeyers theshiftingdemographiclandscapeofpandemicinfluenza AT shwetabansal shiftingdemographiclandscapeofpandemicinfluenza AT babakpourbohloul shiftingdemographiclandscapeofpandemicinfluenza AT nathanielhupert shiftingdemographiclandscapeofpandemicinfluenza AT bryangrenfell shiftingdemographiclandscapeofpandemicinfluenza AT laurenancelmeyers shiftingdemographiclandscapeofpandemicinfluenza
_version_	1718413722706247680

The shifting demographic landscape of pandemic influenza.

Ejemplares similares