Butyrate and Class I Histone Deacetylase Inhibitors Promote Differentiation of Neonatal Porcine Islet Cells into Beta Cells

Neonatal porcine islets-like clusters (NPICCs) are a promising source for cell therapy of type 1 diabetes. Freshly isolated NPICCs are composed of progenitor cells and endocrine cells, which undergo a maturation process lasting several weeks until the normal beta cell function has developed. Here, w...

Full description

Saved in:
Bibliographic Details
Main Authors: Yichen Zhang, Yutian Lei, Mohsen Honarpisheh, Elisabeth Kemter, Eckhard Wolf, Jochen Seissler
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
Online Access:https://doaj.org/article/09918cbd73f843e9a9c24c7c4e0b8b74
Tags: Add Tag
No Tags, Be the first to tag this record!