One-site versus two-site phacotrabeculectomy: a prospective randomized study

One-site versus two-site phacotrabeculectomy: a prospective randomized study

Marilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of...

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Autores principales: Moschos MM, Chatziralli IP, Tsatsos M
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2015
Materias:
glaucoma
phacotrabeculectomy
intraocular pressure
Geriatrics
RC952-954.6
Acceso en línea:https://doaj.org/article/0996db7ff438488fb9ae2684d3ac0a91
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spelling oai:doaj.org-article:0996db7ff438488fb9ae2684d3ac0a912021-12-02T00:39:38ZOne-site versus two-site phacotrabeculectomy: a prospective randomized study1178-1998https://doaj.org/article/0996db7ff438488fb9ae2684d3ac0a912015-08-01T00:00:00Zhttps://www.dovepress.com/one-site-versus-two-site-phacotrabeculectomy-anbspprospective-randomiz-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Marilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation.Methods: Thirty-four patients (41 eyes) with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes) or a two-site (19 eyes) combined procedure. One-site approach consisted of a standard superior phacotrabeculectomy with a limbus-based conjunctival flap, while two-site approach consisted of a clear cornea phacoemulsification and a separate superior trabeculectomy with a limbus-based conjunctival flap.Results: Mean follow-up period was 54 months (standard deviation [SD] 2.3). Mean preoperative intraocular pressure (IOP) in the one-site group was 21.3 mmHg (SD 2.8) and in the two-site group was 21.8 mmHg (SD 3.0) (P>0.1). Mean postoperative IOP significantly decreased in both groups compared to the preoperative level and was 15.6 mmHg (SD 3.5) in the one-site group and 14.9 mmHg (SD 2.7) in the two-site group. Three months later, the difference between the two groups was not statistically significant (P=0.058). The one-site group required significantly more medications than the two-site group (P=0.03). Best-corrected visual acuity (BCVA) improved similarly in both groups, but there was less postoperative (induced) astigmatism in the two-site group in a marginal statistical level (P=0.058). Intra- and postoperative complications were comparable in the two groups.Conclusion: Both techniques yielded similar results concerning final BCVA and IOP reduction. However, the two-site group had less induced astigmatism and a better postoperative IOP control with less required postoperative antiglaucoma medications compared to the one-site group. Keywords: glaucoma, filtering surgery, intraocular pressureMoschos MMChatziralli IPTsatsos MDove Medical Pressarticleglaucomaphacotrabeculectomyintraocular pressureGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 1393-1399 (2015)
institution DOAJ
collection DOAJ
language EN
topic glaucoma
phacotrabeculectomy
intraocular pressure
Geriatrics
RC952-954.6
spellingShingle glaucoma
phacotrabeculectomy
intraocular pressure
Geriatrics
RC952-954.6
Moschos MM
Chatziralli IP
Tsatsos M
One-site versus two-site phacotrabeculectomy: a prospective randomized study
description Marilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation.Methods: Thirty-four patients (41 eyes) with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes) or a two-site (19 eyes) combined procedure. One-site approach consisted of a standard superior phacotrabeculectomy with a limbus-based conjunctival flap, while two-site approach consisted of a clear cornea phacoemulsification and a separate superior trabeculectomy with a limbus-based conjunctival flap.Results: Mean follow-up period was 54 months (standard deviation [SD] 2.3). Mean preoperative intraocular pressure (IOP) in the one-site group was 21.3 mmHg (SD 2.8) and in the two-site group was 21.8 mmHg (SD 3.0) (P>0.1). Mean postoperative IOP significantly decreased in both groups compared to the preoperative level and was 15.6 mmHg (SD 3.5) in the one-site group and 14.9 mmHg (SD 2.7) in the two-site group. Three months later, the difference between the two groups was not statistically significant (P=0.058). The one-site group required significantly more medications than the two-site group (P=0.03). Best-corrected visual acuity (BCVA) improved similarly in both groups, but there was less postoperative (induced) astigmatism in the two-site group in a marginal statistical level (P=0.058). Intra- and postoperative complications were comparable in the two groups.Conclusion: Both techniques yielded similar results concerning final BCVA and IOP reduction. However, the two-site group had less induced astigmatism and a better postoperative IOP control with less required postoperative antiglaucoma medications compared to the one-site group. Keywords: glaucoma, filtering surgery, intraocular pressure
format article
author Moschos MM
Chatziralli IP
Tsatsos M
author_facet Moschos MM
Chatziralli IP
Tsatsos M
author_sort Moschos MM
title One-site versus two-site phacotrabeculectomy: a prospective randomized study
title_short One-site versus two-site phacotrabeculectomy: a prospective randomized study
title_full One-site versus two-site phacotrabeculectomy: a prospective randomized study
title_fullStr One-site versus two-site phacotrabeculectomy: a prospective randomized study
title_full_unstemmed One-site versus two-site phacotrabeculectomy: a prospective randomized study
title_sort one-site versus two-site phacotrabeculectomy: a prospective randomized study
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/0996db7ff438488fb9ae2684d3ac0a91
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AT chatziralliip onesiteversustwositephacotrabeculectomyanbspprospectiverandomizedstudy
AT tsatsosm onesiteversustwositephacotrabeculectomyanbspprospectiverandomizedstudy
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