Hyperlipidemia-induced cholesterol crystal production by endothelial cells promotes atherogenesis
Atherosclerosis is characterized by subendothelial lipid retention believed to be the result of endothelial trancytosis. Here, the authors show that endothelium can take up and process LDL, generating cholesterol crystals that are deposited on the basolateral side of the cells, causing their dysfunc...
Guardado en:
Autores principales: | Yvonne Baumer, Sara McCurdy, Tina M. Weatherby, Nehal N. Mehta, Stefan Halbherr, Pascal Halbherr, Noboru Yamazaki, William A. Boisvert |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/09a229c662fe4fe4a530175d5d4ee89e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Diversity of Lipid Function in Atherogenesis: A Focus on Endothelial Mechanobiology
por: Stanislav Kotlyarov
Publicado: (2021) -
Roles of Macrophages in Atherogenesis
por: Lia Farahi, et al.
Publicado: (2021) -
IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis
por: Nehal N. Mehta, et al.
Publicado: (2017) -
Swiprosin-1 deficiency in macrophages alleviated atherogenesis
por: Ling-Chang Tong, et al.
Publicado: (2021) -
Lipid peroxidation and antioxidants in hyperlipidemia and hypertension
por: MORIEL,PATRICIA, et al.
Publicado: (2000)