Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features
CTCF mediates long-range chromatin interactions which are important for genome organization and function. Here, the authors demonstrate that CTCF-mediated interactome exhibits extensive plasticity and present Lollipop, a machine-learning framework which predicts CTCF-mediated long-range interactions...
Enregistré dans:
Auteurs principaux: | Yan Kai, Jaclyn Andricovich, Zhouhao Zeng, Jun Zhu, Alexandros Tzatsos, Weiqun Peng |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/09a575151e5e4ef0b2ce4b14003d0c4c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice
par: Stephanie Perkail, et autres
Publié: (2020) -
Epigenome editing strategies for the functional annotation of CTCF insulators
par: Daniel R. Tarjan, et autres
Publié: (2019) -
Genomic Marks Associated with Chromatin Compartments in the CTCF, RNAPII Loop and Genomic Windows
par: Teresa Szczepińska, et autres
Publié: (2021) -
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis
par: Jiao Li, et autres
Publié: (2019) -
Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data
par: Yang Wu, et autres
Publié: (2020)