Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism

Here, Robert-Paganin et al. show that myosin A from Plasmodium falciparum is critical for red blood cell invasion and that non-canonical interactions and regulated phosphorylation are important for force generation during parasite invasion.

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Autores principales: Julien Robert-Paganin, James P. Robblee, Daniel Auguin, Thomas C. A. Blake, Carol S. Bookwalter, Elena B. Krementsova, Dihia Moussaoui, Michael J. Previs, Guillaume Jousset, Jake Baum, Kathleen M. Trybus, Anne Houdusse
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/09a7260cc76747dbb13cb2f561bcbfc8
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spelling oai:doaj.org-article:09a7260cc76747dbb13cb2f561bcbfc82021-12-02T16:57:52ZPlasmodium myosin A drives parasite invasion by an atypical force generating mechanism10.1038/s41467-019-11120-02041-1723https://doaj.org/article/09a7260cc76747dbb13cb2f561bcbfc82019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11120-0https://doaj.org/toc/2041-1723Here, Robert-Paganin et al. show that myosin A from Plasmodium falciparum is critical for red blood cell invasion and that non-canonical interactions and regulated phosphorylation are important for force generation during parasite invasion.Julien Robert-PaganinJames P. RobbleeDaniel AuguinThomas C. A. BlakeCarol S. BookwalterElena B. KrementsovaDihia MoussaouiMichael J. PrevisGuillaume JoussetJake BaumKathleen M. TrybusAnne HoudusseNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Julien Robert-Paganin
James P. Robblee
Daniel Auguin
Thomas C. A. Blake
Carol S. Bookwalter
Elena B. Krementsova
Dihia Moussaoui
Michael J. Previs
Guillaume Jousset
Jake Baum
Kathleen M. Trybus
Anne Houdusse
Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism
description Here, Robert-Paganin et al. show that myosin A from Plasmodium falciparum is critical for red blood cell invasion and that non-canonical interactions and regulated phosphorylation are important for force generation during parasite invasion.
format article
author Julien Robert-Paganin
James P. Robblee
Daniel Auguin
Thomas C. A. Blake
Carol S. Bookwalter
Elena B. Krementsova
Dihia Moussaoui
Michael J. Previs
Guillaume Jousset
Jake Baum
Kathleen M. Trybus
Anne Houdusse
author_facet Julien Robert-Paganin
James P. Robblee
Daniel Auguin
Thomas C. A. Blake
Carol S. Bookwalter
Elena B. Krementsova
Dihia Moussaoui
Michael J. Previs
Guillaume Jousset
Jake Baum
Kathleen M. Trybus
Anne Houdusse
author_sort Julien Robert-Paganin
title Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism
title_short Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism
title_full Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism
title_fullStr Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism
title_full_unstemmed Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism
title_sort plasmodium myosin a drives parasite invasion by an atypical force generating mechanism
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/09a7260cc76747dbb13cb2f561bcbfc8
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