Super-resolution label-free volumetric vibrational imaging

Super-resolution microscopy is often limited by photobleaching or uneven distribution of fluorophores. The authors present a label-free superresolution method termed VISTA, combining sample-expansion and vibrational imaging, with resolution down to 78 nm in protein-rich biological structures in cell...

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Autores principales:	Chenxi Qian, Kun Miao, Li-En Lin, Xinhong Chen, Jiajun Du, Lu Wei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/09b14f22491a4a1998ca114b2542a02c
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id	oai:doaj.org-article:09b14f22491a4a1998ca114b2542a02c
record_format	dspace
spelling	oai:doaj.org-article:09b14f22491a4a1998ca114b2542a02c2021-12-02T17:23:48ZSuper-resolution label-free volumetric vibrational imaging10.1038/s41467-021-23951-x2041-1723https://doaj.org/article/09b14f22491a4a1998ca114b2542a02c2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23951-xhttps://doaj.org/toc/2041-1723Super-resolution microscopy is often limited by photobleaching or uneven distribution of fluorophores. The authors present a label-free superresolution method termed VISTA, combining sample-expansion and vibrational imaging, with resolution down to 78 nm in protein-rich biological structures in cells and tissues.Chenxi QianKun MiaoLi-En LinXinhong ChenJiajun DuLu WeiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chenxi Qian Kun Miao Li-En Lin Xinhong Chen Jiajun Du Lu Wei Super-resolution label-free volumetric vibrational imaging
description	Super-resolution microscopy is often limited by photobleaching or uneven distribution of fluorophores. The authors present a label-free superresolution method termed VISTA, combining sample-expansion and vibrational imaging, with resolution down to 78 nm in protein-rich biological structures in cells and tissues.
format	article
author	Chenxi Qian Kun Miao Li-En Lin Xinhong Chen Jiajun Du Lu Wei
author_facet	Chenxi Qian Kun Miao Li-En Lin Xinhong Chen Jiajun Du Lu Wei
author_sort	Chenxi Qian
title	Super-resolution label-free volumetric vibrational imaging
title_short	Super-resolution label-free volumetric vibrational imaging
title_full	Super-resolution label-free volumetric vibrational imaging
title_fullStr	Super-resolution label-free volumetric vibrational imaging
title_full_unstemmed	Super-resolution label-free volumetric vibrational imaging
title_sort	super-resolution label-free volumetric vibrational imaging
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/09b14f22491a4a1998ca114b2542a02c
work_keys_str_mv	AT chenxiqian superresolutionlabelfreevolumetricvibrationalimaging AT kunmiao superresolutionlabelfreevolumetricvibrationalimaging AT lienlin superresolutionlabelfreevolumetricvibrationalimaging AT xinhongchen superresolutionlabelfreevolumetricvibrationalimaging AT jiajundu superresolutionlabelfreevolumetricvibrationalimaging AT luwei superresolutionlabelfreevolumetricvibrationalimaging
_version_	1718380949604925440

Super-resolution label-free volumetric vibrational imaging

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