A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia
Hypoxia is a hallmark of many diseases including cancer and ischemia, and detection can be invasive and of low resolution and specificity. Here the authors show a hypoxia probe that converts non-ionizing light to ultrasound, which enables the acquisition of high-resolution 3D images in deep tissue.
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Nature Portfolio
2017
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oai:doaj.org-article:09d5b01de6d34fcd8e04d433050965b92021-12-02T14:42:25ZA bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia10.1038/s41467-017-01951-02041-1723https://doaj.org/article/09d5b01de6d34fcd8e04d433050965b92017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01951-0https://doaj.org/toc/2041-1723Hypoxia is a hallmark of many diseases including cancer and ischemia, and detection can be invasive and of low resolution and specificity. Here the authors show a hypoxia probe that converts non-ionizing light to ultrasound, which enables the acquisition of high-resolution 3D images in deep tissue.Hailey J. KnoxJamila HedhliTae Wook KimKian KhaliliLawrence W. DobruckiJefferson ChanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Hailey J. Knox Jamila Hedhli Tae Wook Kim Kian Khalili Lawrence W. Dobrucki Jefferson Chan A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia |
description |
Hypoxia is a hallmark of many diseases including cancer and ischemia, and detection can be invasive and of low resolution and specificity. Here the authors show a hypoxia probe that converts non-ionizing light to ultrasound, which enables the acquisition of high-resolution 3D images in deep tissue. |
format |
article |
author |
Hailey J. Knox Jamila Hedhli Tae Wook Kim Kian Khalili Lawrence W. Dobrucki Jefferson Chan |
author_facet |
Hailey J. Knox Jamila Hedhli Tae Wook Kim Kian Khalili Lawrence W. Dobrucki Jefferson Chan |
author_sort |
Hailey J. Knox |
title |
A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia |
title_short |
A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia |
title_full |
A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia |
title_fullStr |
A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia |
title_full_unstemmed |
A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia |
title_sort |
bioreducible n-oxide-based probe for photoacoustic imaging of hypoxia |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/09d5b01de6d34fcd8e04d433050965b9 |
work_keys_str_mv |
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1718389672023949312 |