A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

Hypoxia is a hallmark of many diseases including cancer and ischemia, and detection can be invasive and of low resolution and specificity. Here the authors show a hypoxia probe that converts non-ionizing light to ultrasound, which enables the acquisition of high-resolution 3D images in deep tissue.

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Autores principales: Hailey J. Knox, Jamila Hedhli, Tae Wook Kim, Kian Khalili, Lawrence W. Dobrucki, Jefferson Chan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/09d5b01de6d34fcd8e04d433050965b9
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spelling oai:doaj.org-article:09d5b01de6d34fcd8e04d433050965b92021-12-02T14:42:25ZA bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia10.1038/s41467-017-01951-02041-1723https://doaj.org/article/09d5b01de6d34fcd8e04d433050965b92017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01951-0https://doaj.org/toc/2041-1723Hypoxia is a hallmark of many diseases including cancer and ischemia, and detection can be invasive and of low resolution and specificity. Here the authors show a hypoxia probe that converts non-ionizing light to ultrasound, which enables the acquisition of high-resolution 3D images in deep tissue.Hailey J. KnoxJamila HedhliTae Wook KimKian KhaliliLawrence W. DobruckiJefferson ChanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hailey J. Knox
Jamila Hedhli
Tae Wook Kim
Kian Khalili
Lawrence W. Dobrucki
Jefferson Chan
A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia
description Hypoxia is a hallmark of many diseases including cancer and ischemia, and detection can be invasive and of low resolution and specificity. Here the authors show a hypoxia probe that converts non-ionizing light to ultrasound, which enables the acquisition of high-resolution 3D images in deep tissue.
format article
author Hailey J. Knox
Jamila Hedhli
Tae Wook Kim
Kian Khalili
Lawrence W. Dobrucki
Jefferson Chan
author_facet Hailey J. Knox
Jamila Hedhli
Tae Wook Kim
Kian Khalili
Lawrence W. Dobrucki
Jefferson Chan
author_sort Hailey J. Knox
title A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia
title_short A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia
title_full A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia
title_fullStr A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia
title_full_unstemmed A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia
title_sort bioreducible n-oxide-based probe for photoacoustic imaging of hypoxia
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/09d5b01de6d34fcd8e04d433050965b9
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