A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.

<h4>Background</h4>The growth of stem cells in in vitro conditions requires optimal balance between signals mediating cell survival, proliferation, and self-renewal. For clinical application of stem cells, the use of completely defined conditions and elimination of all animal-derived mat...

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Main Authors: Kristiina Rajala, Bettina Lindroos, Samer M Hussein, Riikka S Lappalainen, Mari Pekkanen-Mattila, Jose Inzunza, Björn Rozell, Susanna Miettinen, Susanna Narkilahti, Erja Kerkelä, Katriina Aalto-Setälä, Timo Otonkoski, Riitta Suuronen, Outi Hovatta, Heli Skottman
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
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Online Access:https://doaj.org/article/09d81d884d8f48b8b44d6709c03d6eff
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