BCG therapy is associated with long-term, durable induction of Treg signature genes by epigenetic modulation

BCG therapy is associated with long-term, durable induction of Treg signature genes by epigenetic modulation

Abstract Induction of immunosuppressive T-regulatory cells (Tregs) is a desirable goal in autoimmunity, and perhaps other immune diseases of activation. One promising avenue is with the bacille-calmette-guérin (BCG) vaccine in autoimmune type 1 diabetes (T1D). Its administration is associated with g...

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Autores principales: Ryan C. Keefe, Hiroyuki Takahashi, Lisa Tran, Kacie Nelson, Nathan Ng, Willem M. Kühtreiber, Denise L. Faustman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/09f73d65921c45aab18448f13edbdcdf
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