Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast

Squamous cell carcinoma (SCC) of the breast is a rare malignancy that usually has a triple-negative phenotype and poor clinical outcomes. Because HER2-positive SCC of the breast is extremely rare, its clinicopathologic features are understudied, and the effects of neoadjuvant chemotherapy including...

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Autores principales:	Yuki Usui, Ryoichi Matsunuma, Kei Yamaguchi, Ryosuke Hayami, Aya Muramatsu, Makoto Suzuki, Michiko Tsuneizumi
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	pathological complete response breast cancer squamous cell carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/09fd35ec4759494b829fca657c485bbb
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spelling	oai:doaj.org-article:09fd35ec4759494b829fca657c485bbb2021-11-18T11:08:46ZPathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast1662-657510.1159/000519746https://doaj.org/article/09fd35ec4759494b829fca657c485bbb2021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/519746https://doaj.org/toc/1662-6575Squamous cell carcinoma (SCC) of the breast is a rare malignancy that usually has a triple-negative phenotype and poor clinical outcomes. Because HER2-positive SCC of the breast is extremely rare, its clinicopathologic features are understudied, and the effects of neoadjuvant chemotherapy including anti-HER2-targeted therapy on the tumor are unclear, although treatment resistance was described in some reports. In this study, we reported a case of HER2-positive SCC of the breast in which a pathological complete response to neoadjuvant chemotherapy was observed.Yuki UsuiRyoichi MatsunumaKei YamaguchiRyosuke HayamiAya MuramatsuMakoto SuzukiMichiko TsuneizumiKarger Publishersarticlepathological complete responsebreast cancersquamous cell carcinomaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCase Reports in Oncology, Vol 14, Iss 3, Pp 1536-1541 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	pathological complete response breast cancer squamous cell carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	pathological complete response breast cancer squamous cell carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Yuki Usui Ryoichi Matsunuma Kei Yamaguchi Ryosuke Hayami Aya Muramatsu Makoto Suzuki Michiko Tsuneizumi Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast
description	Squamous cell carcinoma (SCC) of the breast is a rare malignancy that usually has a triple-negative phenotype and poor clinical outcomes. Because HER2-positive SCC of the breast is extremely rare, its clinicopathologic features are understudied, and the effects of neoadjuvant chemotherapy including anti-HER2-targeted therapy on the tumor are unclear, although treatment resistance was described in some reports. In this study, we reported a case of HER2-positive SCC of the breast in which a pathological complete response to neoadjuvant chemotherapy was observed.
format	article
author	Yuki Usui Ryoichi Matsunuma Kei Yamaguchi Ryosuke Hayami Aya Muramatsu Makoto Suzuki Michiko Tsuneizumi
author_facet	Yuki Usui Ryoichi Matsunuma Kei Yamaguchi Ryosuke Hayami Aya Muramatsu Makoto Suzuki Michiko Tsuneizumi
author_sort	Yuki Usui
title	Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast
title_short	Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast
title_full	Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast
title_fullStr	Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast
title_full_unstemmed	Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast
title_sort	pathological complete response to neoadjuvant chemotherapy in a patient with her2-positive squamous cell carcinoma of the breast
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/09fd35ec4759494b829fca657c485bbb
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Pathological Complete Response to Neoadjuvant Chemotherapy in a Patient with HER2-Positive Squamous Cell Carcinoma of the Breast

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