Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors

Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution an...

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Autores principales: Michael Taeyoung Hwang, Mohammad Heiranian, Yerim Kim, Seungyong You, Juyoung Leem, Amir Taqieddin, Vahid Faramarzi, Yuhang Jing, Insu Park, Arend M. van der Zande, Sungwoo Nam, Narayana R. Aluru, Rashid Bashir
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0a110dbfc3c94886aa1f75a27c37a285
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Sumario:Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution and ~600 molecules in human serum.