Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors

Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution an...

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Autores principales: Michael Taeyoung Hwang, Mohammad Heiranian, Yerim Kim, Seungyong You, Juyoung Leem, Amir Taqieddin, Vahid Faramarzi, Yuhang Jing, Insu Park, Arend M. van der Zande, Sungwoo Nam, Narayana R. Aluru, Rashid Bashir
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0a110dbfc3c94886aa1f75a27c37a285
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spelling oai:doaj.org-article:0a110dbfc3c94886aa1f75a27c37a2852021-12-02T16:50:03ZUltrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors10.1038/s41467-020-15330-92041-1723https://doaj.org/article/0a110dbfc3c94886aa1f75a27c37a2852020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15330-9https://doaj.org/toc/2041-1723Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution and ~600 molecules in human serum.Michael Taeyoung HwangMohammad HeiranianYerim KimSeungyong YouJuyoung LeemAmir TaqieddinVahid FaramarziYuhang JingInsu ParkArend M. van der ZandeSungwoo NamNarayana R. AluruRashid BashirNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Michael Taeyoung Hwang
Mohammad Heiranian
Yerim Kim
Seungyong You
Juyoung Leem
Amir Taqieddin
Vahid Faramarzi
Yuhang Jing
Insu Park
Arend M. van der Zande
Sungwoo Nam
Narayana R. Aluru
Rashid Bashir
Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
description Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution and ~600 molecules in human serum.
format article
author Michael Taeyoung Hwang
Mohammad Heiranian
Yerim Kim
Seungyong You
Juyoung Leem
Amir Taqieddin
Vahid Faramarzi
Yuhang Jing
Insu Park
Arend M. van der Zande
Sungwoo Nam
Narayana R. Aluru
Rashid Bashir
author_facet Michael Taeyoung Hwang
Mohammad Heiranian
Yerim Kim
Seungyong You
Juyoung Leem
Amir Taqieddin
Vahid Faramarzi
Yuhang Jing
Insu Park
Arend M. van der Zande
Sungwoo Nam
Narayana R. Aluru
Rashid Bashir
author_sort Michael Taeyoung Hwang
title Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
title_short Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
title_full Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
title_fullStr Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
title_full_unstemmed Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
title_sort ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/0a110dbfc3c94886aa1f75a27c37a285
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