Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation

Abstract We assessed the discontinuation rate and the reason for discontinuation of common contraceptives used by reproductive-aged Thai women. We recruited 1880 women aged 18–45 years from the Family Planning Clinic of the Chulalongkorn Hospital in Bangkok. The participants were followed at three,...

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Autores principales:	Unnop Jaisamrarn, Monchai Santipap, Somsook Santibenchakul
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0a1b03d60f034b7380edf55c2d007995
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spelling	oai:doaj.org-article:0a1b03d60f034b7380edf55c2d0079952021-12-02T16:53:01ZDiscontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation10.1038/s41598-021-90373-62045-2322https://doaj.org/article/0a1b03d60f034b7380edf55c2d0079952021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90373-6https://doaj.org/toc/2045-2322Abstract We assessed the discontinuation rate and the reason for discontinuation of common contraceptives used by reproductive-aged Thai women. We recruited 1880 women aged 18–45 years from the Family Planning Clinic of the Chulalongkorn Hospital in Bangkok. The participants were followed at three, six and twelve months. A Cox proportional hazards model was used to determine personal risks of discontinuing contraceptives. The incidence rate for discontinuation of combined oral contraceptive pills (COCs), depot medroxyprogesterone acetate (DMPA), copper intrauterine device (IUD), and contraceptive implant(s) were 21.3, 9.2, 4.4, and 2.3/100 person-years, respectively. Most of the women who discontinued (185/222) discontinued contraceptives due to side effects. Compared to contraceptive implant users, the adjusted hazard ratios (aHRs) [95% confidence intervals (CIs)] of discontinuing COCs, DMPA, and the copper IUD were 9.6 (4.3–21.8), 4.2 (1.8–10.0), and 2.2 (0.8–5.9), respectively. Lower income, higher parity, history of miscarriage, and history of abortion were independent predictors of contraceptive discontinuation in a multivariable model.Unnop JaisamrarnMonchai SantipapSomsook SantibenchakulNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Unnop Jaisamrarn Monchai Santipap Somsook Santibenchakul Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation
description	Abstract We assessed the discontinuation rate and the reason for discontinuation of common contraceptives used by reproductive-aged Thai women. We recruited 1880 women aged 18–45 years from the Family Planning Clinic of the Chulalongkorn Hospital in Bangkok. The participants were followed at three, six and twelve months. A Cox proportional hazards model was used to determine personal risks of discontinuing contraceptives. The incidence rate for discontinuation of combined oral contraceptive pills (COCs), depot medroxyprogesterone acetate (DMPA), copper intrauterine device (IUD), and contraceptive implant(s) were 21.3, 9.2, 4.4, and 2.3/100 person-years, respectively. Most of the women who discontinued (185/222) discontinued contraceptives due to side effects. Compared to contraceptive implant users, the adjusted hazard ratios (aHRs) [95% confidence intervals (CIs)] of discontinuing COCs, DMPA, and the copper IUD were 9.6 (4.3–21.8), 4.2 (1.8–10.0), and 2.2 (0.8–5.9), respectively. Lower income, higher parity, history of miscarriage, and history of abortion were independent predictors of contraceptive discontinuation in a multivariable model.
format	article
author	Unnop Jaisamrarn Monchai Santipap Somsook Santibenchakul
author_facet	Unnop Jaisamrarn Monchai Santipap Somsook Santibenchakul
author_sort	Unnop Jaisamrarn
title	Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation
title_short	Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation
title_full	Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation
title_fullStr	Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation
title_full_unstemmed	Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation
title_sort	discontinuation rates of different contraceptive methods in thai women up to 1-year after method initiation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0a1b03d60f034b7380edf55c2d007995
work_keys_str_mv	AT unnopjaisamrarn discontinuationratesofdifferentcontraceptivemethodsinthaiwomenupto1yearaftermethodinitiation AT monchaisantipap discontinuationratesofdifferentcontraceptivemethodsinthaiwomenupto1yearaftermethodinitiation AT somsooksantibenchakul discontinuationratesofdifferentcontraceptivemethodsinthaiwomenupto1yearaftermethodinitiation
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Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation

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