Sequential actions of EOMES and T-BET promote stepwise maturation of natural killer cells

Sequential actions of EOMES and T-BET promote stepwise maturation of natural killer cells

Natural Killer cell development is controlled by two related transcription factors, Eomes and T-bet. Authors show here that while the two factors share a large proportion of their target genes, they regulate distinct developmental processes by differing in their pattern of expression and in their as...

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Autores principales: Jiang Zhang, Stéphanie Le Gras, Kevin Pouxvielh, Fabrice Faure, Lucie Fallone, Nicolas Kern, Marion Moreews, Anne-Laure Mathieu, Raphaël Schneider, Quentin Marliac, Mathieu Jung, Aurore Berton, Simon Hayek, Pierre-Olivier Vidalain, Antoine Marçais, Garvin Dodard, Anne Dejean, Laurent Brossay, Yad Ghavi-Helm, Thierry Walzer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/0a1b6ee2a9a04c48998d4f888c12b930
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