SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus

Using SARS-CoV-2-specific antibody- and neutralization assays, Dogan et al find that hospitalized individuals show higher IgG antibody responses and higher neutralization titers compared to outpatient or convalescent plasma donors, providing insights into the host humoral response to SARS CoV-2.

Guardado en:
Detalles Bibliográficos
Autores principales: Mikail Dogan, Lina Kozhaya, Lindsey Placek, Courtney Gunter, Mesut Yigit, Rachel Hardy, Matthew Plassmeyer, Paige Coatney, Kimberleigh Lillard, Zaheer Bukhari, Michael Kleinberg, Chelsea Hayes, Moshe Arditi, Ellen Klapper, Noah Merin, Bruce Tsan-Tang Liang, Raavi Gupta, Oral Alpan, Derya Unutmaz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Acceso en línea:https://doaj.org/article/0a236342fbca4be7ad7450120dc25e6b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:0a236342fbca4be7ad7450120dc25e6b
record_format dspace
spelling oai:doaj.org-article:0a236342fbca4be7ad7450120dc25e6b2021-12-02T13:57:24ZSARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus10.1038/s42003-021-01649-62399-3642https://doaj.org/article/0a236342fbca4be7ad7450120dc25e6b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01649-6https://doaj.org/toc/2399-3642Using SARS-CoV-2-specific antibody- and neutralization assays, Dogan et al find that hospitalized individuals show higher IgG antibody responses and higher neutralization titers compared to outpatient or convalescent plasma donors, providing insights into the host humoral response to SARS CoV-2.Mikail DoganLina KozhayaLindsey PlacekCourtney GunterMesut YigitRachel HardyMatthew PlassmeyerPaige CoatneyKimberleigh LillardZaheer BukhariMichael KleinbergChelsea HayesMoshe ArditiEllen KlapperNoah MerinBruce Tsan-Tang LiangRaavi GuptaOral AlpanDerya UnutmazNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Mikail Dogan
Lina Kozhaya
Lindsey Placek
Courtney Gunter
Mesut Yigit
Rachel Hardy
Matthew Plassmeyer
Paige Coatney
Kimberleigh Lillard
Zaheer Bukhari
Michael Kleinberg
Chelsea Hayes
Moshe Arditi
Ellen Klapper
Noah Merin
Bruce Tsan-Tang Liang
Raavi Gupta
Oral Alpan
Derya Unutmaz
SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
description Using SARS-CoV-2-specific antibody- and neutralization assays, Dogan et al find that hospitalized individuals show higher IgG antibody responses and higher neutralization titers compared to outpatient or convalescent plasma donors, providing insights into the host humoral response to SARS CoV-2.
format article
author Mikail Dogan
Lina Kozhaya
Lindsey Placek
Courtney Gunter
Mesut Yigit
Rachel Hardy
Matthew Plassmeyer
Paige Coatney
Kimberleigh Lillard
Zaheer Bukhari
Michael Kleinberg
Chelsea Hayes
Moshe Arditi
Ellen Klapper
Noah Merin
Bruce Tsan-Tang Liang
Raavi Gupta
Oral Alpan
Derya Unutmaz
author_facet Mikail Dogan
Lina Kozhaya
Lindsey Placek
Courtney Gunter
Mesut Yigit
Rachel Hardy
Matthew Plassmeyer
Paige Coatney
Kimberleigh Lillard
Zaheer Bukhari
Michael Kleinberg
Chelsea Hayes
Moshe Arditi
Ellen Klapper
Noah Merin
Bruce Tsan-Tang Liang
Raavi Gupta
Oral Alpan
Derya Unutmaz
author_sort Mikail Dogan
title SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
title_short SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
title_full SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
title_fullStr SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
title_full_unstemmed SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
title_sort sars-cov-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0a236342fbca4be7ad7450120dc25e6b
work_keys_str_mv AT mikaildogan sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT linakozhaya sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT lindseyplacek sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT courtneygunter sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT mesutyigit sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT rachelhardy sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT matthewplassmeyer sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT paigecoatney sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT kimberleighlillard sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT zaheerbukhari sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT michaelkleinberg sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT chelseahayes sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT moshearditi sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT ellenklapper sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT noahmerin sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT brucetsantangliang sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT raavigupta sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT oralalpan sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
AT deryaunutmaz sarscov2specificantibodyandneutralizationassaysrevealthewiderangeofthehumoralimmuneresponsetovirus
_version_ 1718392301425786880