TGF-β/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos.

TGF-β/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos.

The Transforming Growth Factor-β (TGF-β) signaling pathway is one of the major pathways essential for normal embryonic development and tissue homeostasis, with anti-tumor but also pro-metastatic properties in cancer. This pathway directly regulates several target genes that mediate its downstream fu...

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Bibliographic Details
Main Authors: Nicholas Redshaw, Carme Camps, Vikas Sharma, Mehdi Motallebipour, Marcela Guzman-Ayala, Spyros Oikonomopoulos, Efstathia Thymiakou, Jiannis Ragoussis, Vasso Episkopou
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/0a2eba45ff01472ab54a4c533d4d69f3
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