Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells

Objective. Stem cell therapy, specifically, pre-induction of mesenchymal stem cells toward male germ-like cells may be useful in patients with azoospermia. The aim of this study was to evaluate in vitro differentiation of mouse bone marrow-derived mesenchymal stem cells (BMSCs) into male germ-like c...

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Autores principales:	Malekmohamadi Nasim, Abdanipour Alireza, Ghorbanlou Mehrdad, Shokri Saeed, Shirazi Reza, Dimitriadis Eva, Nejatbakhsh Reza
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2019
Materias:	bmscs bone morphogenetic protein 4 indirect co-culture stra8 dazl Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/0a331bb941354c94a01edafd49bf2c00
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id	oai:doaj.org-article:0a331bb941354c94a01edafd49bf2c00
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spelling	oai:doaj.org-article:0a331bb941354c94a01edafd49bf2c002021-12-02T16:41:14ZDifferentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells1336-032910.2478/enr-2019-0011https://doaj.org/article/0a331bb941354c94a01edafd49bf2c002019-04-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0011https://doaj.org/toc/1336-0329Objective. Stem cell therapy, specifically, pre-induction of mesenchymal stem cells toward male germ-like cells may be useful in patients with azoospermia. The aim of this study was to evaluate in vitro differentiation of mouse bone marrow-derived mesenchymal stem cells (BMSCs) into male germ-like cells by indirect co-culture with testicular cells in the presence of bone morphogenetic protein 4 (BMP4).Malekmohamadi NasimAbdanipour AlirezaGhorbanlou MehrdadShokri SaeedShirazi RezaDimitriadis EvaNejatbakhsh RezaSciendoarticlebmscsbone morphogenetic protein 4indirect co-culturestra8dazlDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 2, Pp 93-99 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	bmscs bone morphogenetic protein 4 indirect co-culture stra8 dazl Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	bmscs bone morphogenetic protein 4 indirect co-culture stra8 dazl Diseases of the endocrine glands. Clinical endocrinology RC648-665 Malekmohamadi Nasim Abdanipour Alireza Ghorbanlou Mehrdad Shokri Saeed Shirazi Reza Dimitriadis Eva Nejatbakhsh Reza Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells
description	Objective. Stem cell therapy, specifically, pre-induction of mesenchymal stem cells toward male germ-like cells may be useful in patients with azoospermia. The aim of this study was to evaluate in vitro differentiation of mouse bone marrow-derived mesenchymal stem cells (BMSCs) into male germ-like cells by indirect co-culture with testicular cells in the presence of bone morphogenetic protein 4 (BMP4).
format	article
author	Malekmohamadi Nasim Abdanipour Alireza Ghorbanlou Mehrdad Shokri Saeed Shirazi Reza Dimitriadis Eva Nejatbakhsh Reza
author_facet	Malekmohamadi Nasim Abdanipour Alireza Ghorbanlou Mehrdad Shokri Saeed Shirazi Reza Dimitriadis Eva Nejatbakhsh Reza
author_sort	Malekmohamadi Nasim
title	Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells
title_short	Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells
title_full	Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells
title_fullStr	Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells
title_full_unstemmed	Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells
title_sort	differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells
publisher	Sciendo
publishDate	2019
url	https://doaj.org/article/0a331bb941354c94a01edafd49bf2c00
work_keys_str_mv	AT malekmohamadinasim differentiationofbonemarrowderivedmesenchymalstemcellsintomalegermlikecellsincoculturewithtesticularcells AT abdanipouralireza differentiationofbonemarrowderivedmesenchymalstemcellsintomalegermlikecellsincoculturewithtesticularcells AT ghorbanloumehrdad differentiationofbonemarrowderivedmesenchymalstemcellsintomalegermlikecellsincoculturewithtesticularcells AT shokrisaeed differentiationofbonemarrowderivedmesenchymalstemcellsintomalegermlikecellsincoculturewithtesticularcells AT shirazireza differentiationofbonemarrowderivedmesenchymalstemcellsintomalegermlikecellsincoculturewithtesticularcells AT dimitriadiseva differentiationofbonemarrowderivedmesenchymalstemcellsintomalegermlikecellsincoculturewithtesticularcells AT nejatbakhshreza differentiationofbonemarrowderivedmesenchymalstemcellsintomalegermlikecellsincoculturewithtesticularcells
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Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells

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