An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry

Abstract Emerging evidence suggests that a diagnosis of cutaneous melanoma (CM) may be associated with prostate cancer (PC) incidence. We examined if the incidence of CM was associated with an increased subsequent risk of PC. We used data from the New South Wales Cancer Registry for all CM and PC ca...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	D. Cole-Clark, V. Nair-Shalliker, A. Bang, K. Rasiah, V. Chalasani, D. P. Smith
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0a488957ec1a42aa8d0704a24b3e170c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0a488957ec1a42aa8d0704a24b3e170c
record_format	dspace
spelling	oai:doaj.org-article:0a488957ec1a42aa8d0704a24b3e170c2021-12-02T15:09:04ZAn initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry10.1038/s41598-018-25408-62045-2322https://doaj.org/article/0a488957ec1a42aa8d0704a24b3e170c2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25408-6https://doaj.org/toc/2045-2322Abstract Emerging evidence suggests that a diagnosis of cutaneous melanoma (CM) may be associated with prostate cancer (PC) incidence. We examined if the incidence of CM was associated with an increased subsequent risk of PC. We used data from the New South Wales Cancer Registry for all CM and PC cases diagnosed between January 1972 and December 2008. We calculated the age standardized incidence ratio (SIR) and 95% confidence intervals (95% CI) for PC incidence following a CM diagnosis, applying age- and calendar- specific rates to the appropriate person years at risk. We determined rate ratio (RR) and 95% CI of PC incidence according to specified socio-demographic categories and disease related characteristics, using a negative binomial model. There were 143,594 men diagnosed with PC or CM in the study period and of these 101,198 and 42,396 were diagnosed with PC and CM, respectively, as first primary cancers. Risk of PC incidence increased following CM diagnosis (n = 2,114; SIR = 1.25; 95% CI:1.20.8-1.31: p < 0.0001), with the increased risk apparent in men diagnosed with localised CM (n = 1,862;SIR = 1.26; 95% CI:1.20–1.32). CM diagnosis increased the subsequent risk of PC incidence. This raises the potential for future PC risk to be discussed with newly diagnosed males with CM.D. Cole-ClarkV. Nair-ShallikerA. BangK. RasiahV. ChalasaniD. P. SmithNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q D. Cole-Clark V. Nair-Shalliker A. Bang K. Rasiah V. Chalasani D. P. Smith An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry
description	Abstract Emerging evidence suggests that a diagnosis of cutaneous melanoma (CM) may be associated with prostate cancer (PC) incidence. We examined if the incidence of CM was associated with an increased subsequent risk of PC. We used data from the New South Wales Cancer Registry for all CM and PC cases diagnosed between January 1972 and December 2008. We calculated the age standardized incidence ratio (SIR) and 95% confidence intervals (95% CI) for PC incidence following a CM diagnosis, applying age- and calendar- specific rates to the appropriate person years at risk. We determined rate ratio (RR) and 95% CI of PC incidence according to specified socio-demographic categories and disease related characteristics, using a negative binomial model. There were 143,594 men diagnosed with PC or CM in the study period and of these 101,198 and 42,396 were diagnosed with PC and CM, respectively, as first primary cancers. Risk of PC incidence increased following CM diagnosis (n = 2,114; SIR = 1.25; 95% CI:1.20.8-1.31: p < 0.0001), with the increased risk apparent in men diagnosed with localised CM (n = 1,862;SIR = 1.26; 95% CI:1.20–1.32). CM diagnosis increased the subsequent risk of PC incidence. This raises the potential for future PC risk to be discussed with newly diagnosed males with CM.
format	article
author	D. Cole-Clark V. Nair-Shalliker A. Bang K. Rasiah V. Chalasani D. P. Smith
author_facet	D. Cole-Clark V. Nair-Shalliker A. Bang K. Rasiah V. Chalasani D. P. Smith
author_sort	D. Cole-Clark
title	An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry
title_short	An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry
title_full	An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry
title_fullStr	An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry
title_full_unstemmed	An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry
title_sort	initial melanoma diagnosis may increase the subsequent risk of prostate cancer: results from the new south wales cancer registry
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0a488957ec1a42aa8d0704a24b3e170c
work_keys_str_mv	AT dcoleclark aninitialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT vnairshalliker aninitialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT abang aninitialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT krasiah aninitialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT vchalasani aninitialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT dpsmith aninitialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT dcoleclark initialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT vnairshalliker initialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT abang initialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT krasiah initialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT vchalasani initialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry AT dpsmith initialmelanomadiagnosismayincreasethesubsequentriskofprostatecancerresultsfromthenewsouthwalescancerregistry
_version_	1718387917742669824

An initial melanoma diagnosis may increase the subsequent risk of prostate cancer: Results from the New South Wales Cancer Registry

Ejemplares similares