Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis

Objective. To analyze the clinical incidence, clinical manifestations, laboratory examination, and complications of Sjogren’s syndrome complicated with thyroid disorders in patients and to explore the clinical significance of its occurrence and concurrence relationship. Methods. The clinical manifes...

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Autores principales:	Min Dai, Jing Wang, Qian Huang
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Medicine (General) R5-920 Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/0a5630e056ce4264b67d40746aff4299
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spelling	oai:doaj.org-article:0a5630e056ce4264b67d40746aff42992021-11-08T02:37:14ZClinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis2040-230910.1155/2021/2280070https://doaj.org/article/0a5630e056ce4264b67d40746aff42992021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2280070https://doaj.org/toc/2040-2309Objective. To analyze the clinical incidence, clinical manifestations, laboratory examination, and complications of Sjogren’s syndrome complicated with thyroid disorders in patients and to explore the clinical significance of its occurrence and concurrence relationship. Methods. The clinical manifestations, thyroid function, antithyroid antibodies, immunology indicators, autoantibodies, and routine laboratory examination items of 201 patients with Sjogren’s syndrome in Chongqing Hospital of Traditional Chinese Medicine were reviewed and analyzed. According to whether the thyroid function was abnormal or not, the patients were divided into the group of Sjogren’s syndrome complicated with abnormal thyroid function (n = 36) and the group of Sjogren’s syndrome without abnormal thyroid function (n = 165). The clinical symptoms and test indicators of the two groups were compared. Results. Among 201 patients with Sjogren’s syndrome, 36 patients had abnormal thyroid function (17.9%) and 36 patients with abnormal thyroid function had hypothyroidism. The abnormal renal function, decreased Hb, decreased WBC, increased ESR, and decreased C4 were more significant in the group with Sjogren’s syndrome complicated with abnormal thyroid function, which had significant differences compared with the group with normal thyroid function (P<0.05). The positive rates of aTG and aTPO in patients with Sjogren’s syndrome complicated with thyroid disorders were higher than that in the normal group, and the difference between the two groups was statistically significant (P<0.05). Conclusion. Patients with Sjogren’s syndrome are often associated with hypothyroidism, and these patients may have more severe immune disorders, anemia, leukopenia, and renal involvement. The results show that paying attention to the detection of thyroid function in patients with Sjogren’s syndrome may be of positive significance to judge the condition and prognosis.Min DaiJing WangQian HuangHindawi LimitedarticleMedicine (General)R5-920Medical technologyR855-855.5ENJournal of Healthcare Engineering, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920 Medical technology R855-855.5
spellingShingle	Medicine (General) R5-920 Medical technology R855-855.5 Min Dai Jing Wang Qian Huang Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis
description	Objective. To analyze the clinical incidence, clinical manifestations, laboratory examination, and complications of Sjogren’s syndrome complicated with thyroid disorders in patients and to explore the clinical significance of its occurrence and concurrence relationship. Methods. The clinical manifestations, thyroid function, antithyroid antibodies, immunology indicators, autoantibodies, and routine laboratory examination items of 201 patients with Sjogren’s syndrome in Chongqing Hospital of Traditional Chinese Medicine were reviewed and analyzed. According to whether the thyroid function was abnormal or not, the patients were divided into the group of Sjogren’s syndrome complicated with abnormal thyroid function (n = 36) and the group of Sjogren’s syndrome without abnormal thyroid function (n = 165). The clinical symptoms and test indicators of the two groups were compared. Results. Among 201 patients with Sjogren’s syndrome, 36 patients had abnormal thyroid function (17.9%) and 36 patients with abnormal thyroid function had hypothyroidism. The abnormal renal function, decreased Hb, decreased WBC, increased ESR, and decreased C4 were more significant in the group with Sjogren’s syndrome complicated with abnormal thyroid function, which had significant differences compared with the group with normal thyroid function (P<0.05). The positive rates of aTG and aTPO in patients with Sjogren’s syndrome complicated with thyroid disorders were higher than that in the normal group, and the difference between the two groups was statistically significant (P<0.05). Conclusion. Patients with Sjogren’s syndrome are often associated with hypothyroidism, and these patients may have more severe immune disorders, anemia, leukopenia, and renal involvement. The results show that paying attention to the detection of thyroid function in patients with Sjogren’s syndrome may be of positive significance to judge the condition and prognosis.
format	article
author	Min Dai Jing Wang Qian Huang
author_facet	Min Dai Jing Wang Qian Huang
author_sort	Min Dai
title	Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis
title_short	Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis
title_full	Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis
title_fullStr	Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis
title_full_unstemmed	Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis
title_sort	clinical features and laboratory examination results of sjogren’s syndrome complicated with thyroid disorders: a retrospective analysis
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/0a5630e056ce4264b67d40746aff4299
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Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis

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