p38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage
Abstract XRCC1 is a scaffold protein involved in base excision repair and single strand break repair. It is a phosphoprotein that contains more than 45 phosphorylation sites, however only a few of these have been characterized and connected to specific kinases and functions. Mitogen activated protei...
Guardado en:
Autores principales: | Mirta Mittelstedt Leal de Sousa, Karine Øian Bjørås, Audun Hanssen-Bauer, Karin Solvang-Garten, Marit Otterlei |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0a57bba2f3d440368015027c1bad3759 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Phosphopeptide interactions of the Nbs1 N-terminal FHA-BRCT1/2 domains
por: Kyungmin Kim, et al.
Publicado: (2021) -
DNA Repair Genes XRCC1, XRCC3, XPD, and OGG1 Polymorphisms among the Central Region Population of Saudi Arabia
por: Alanazi,Mohammad, et al.
Publicado: (2013) -
Inhibition of HDAC6 alleviating lipopolysaccharide-induced p38MAPK phosphorylation and neuroinflammation in mice
por: Yuanjian Song, et al.
Publicado: (2019) -
Phosphorylation of LAMP2A by p38 MAPK couples ER stress to chaperone-mediated autophagy
por: Wenming Li, et al.
Publicado: (2017) -
Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50
por: Rajan Kumar Choudhary, et al.
Publicado: (2017)