Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface

Abstract Cell surface expression of alpha-enolase, a glycolytic enzyme displaying moonlighting activities, has been shown to contribute to the motility and invasiveness of cancer cells through the protein non-enzymatic function of binding plasminogen and enhancing plasmin formation. Although a few r...

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Bibliographic Details
Main Authors: Giovanni Perconti, Cristina Maranto, Daniele P. Romancino, Patrizia Rubino, Salvatore Feo, Antonella Bongiovanni, Agata Giallongo
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/0a6d5641a63d4e43bbe57e984a44c978
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