Effect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry

Bharkbhum Khambhiphant,1 Suganlaya Sasiwilasagorn,2 Nattida Chatbunchachai,3 Krit Pongpirul2,4 1Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 2Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, 3Department of Ophthalmolo...

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Autores principales: Khambhiphant B, Sasiwilasagorn S, Chatbunchachai N, Pongpirul K
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Lenguaje:EN
Publicado: Dove Medical Press 2016
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spelling oai:doaj.org-article:0a6ffedfcbf34a399f2c84da866267c42021-12-02T00:17:36ZEffect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry1177-5483https://doaj.org/article/0a6ffedfcbf34a399f2c84da866267c42016-07-01T00:00:00Zhttps://www.dovepress.com/effect-of-pupillary-dilation-on-haigis-formula--calculated-intraocular-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Bharkbhum Khambhiphant,1 Suganlaya Sasiwilasagorn,2 Nattida Chatbunchachai,3 Krit Pongpirul2,4 1Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 2Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, 3Department of Ophthalmology, Samut Prakan Hospital, Samut Prakan, Thailand; 4Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA Purpose: The purpose of this study was to evaluate the effect of pupillary dilation on the Haigis formula-calculated intraocular lens (IOL) power and ocular biometry measurements by using IOLMaster®. Methods: A prospective study was performed for biometry measurements of 373 eyes of 192 healthy subjects using the IOLMaster at the outpatient department of King Chulalongkorn Memorial Hospital from February 2013 to July 2013. The axial length (AL), anterior chamber depth (ACD), keratometry (K), and IOL power were measured before and after 1% tropicamide eye drop instillation. The Haigis formula was used in the IOL power calculation with the predicted target to emmetropia. Each parameter was compared by a paired t-test prior to and after pupillary dilation. Bland–Altman plots were also used to determine the agreement between each parameter. Results: The mean age of the subjects was 53.74±14.41 years (range 18–93 years). No differences in AL (P=0.03), steepest K (P=0.42), and flattest K (P=0.41) were obtained from the IOLMaster after pupillary dilation. However, ACD and IOL power were significantly different postdilation (P<0.01 and P<0.01, respectively). In ACD and IOL power measurements, the concordance rates were 93.03% and 97.05% within 95% limits of agreement (-0.48 to 0.26 mm and -1.09 to 0.88 D, respectively) in the Bland–Altman plots. Conclusion: Biometry measurements in the cycloplegic stage should be considered in the IOL formulas that use parameters other than AL and K. Keywords: Haigis formula, intraocular lens, IOLMaster, optical biometry, pupillary dilationKhambhiphant BSasiwilasagorn SChatbunchachai NPongpirul KDove Medical PressarticleHaigis FormulaIntraocular LensIOL masterOptical BiometryPupillary DilationOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 1405-1410 (2016)
institution DOAJ
collection DOAJ
language EN
topic Haigis Formula
Intraocular Lens
IOL master
Optical Biometry
Pupillary Dilation
Ophthalmology
RE1-994
spellingShingle Haigis Formula
Intraocular Lens
IOL master
Optical Biometry
Pupillary Dilation
Ophthalmology
RE1-994
Khambhiphant B
Sasiwilasagorn S
Chatbunchachai N
Pongpirul K
Effect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry
description Bharkbhum Khambhiphant,1 Suganlaya Sasiwilasagorn,2 Nattida Chatbunchachai,3 Krit Pongpirul2,4 1Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 2Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, 3Department of Ophthalmology, Samut Prakan Hospital, Samut Prakan, Thailand; 4Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA Purpose: The purpose of this study was to evaluate the effect of pupillary dilation on the Haigis formula-calculated intraocular lens (IOL) power and ocular biometry measurements by using IOLMaster®. Methods: A prospective study was performed for biometry measurements of 373 eyes of 192 healthy subjects using the IOLMaster at the outpatient department of King Chulalongkorn Memorial Hospital from February 2013 to July 2013. The axial length (AL), anterior chamber depth (ACD), keratometry (K), and IOL power were measured before and after 1% tropicamide eye drop instillation. The Haigis formula was used in the IOL power calculation with the predicted target to emmetropia. Each parameter was compared by a paired t-test prior to and after pupillary dilation. Bland–Altman plots were also used to determine the agreement between each parameter. Results: The mean age of the subjects was 53.74±14.41 years (range 18–93 years). No differences in AL (P=0.03), steepest K (P=0.42), and flattest K (P=0.41) were obtained from the IOLMaster after pupillary dilation. However, ACD and IOL power were significantly different postdilation (P<0.01 and P<0.01, respectively). In ACD and IOL power measurements, the concordance rates were 93.03% and 97.05% within 95% limits of agreement (-0.48 to 0.26 mm and -1.09 to 0.88 D, respectively) in the Bland–Altman plots. Conclusion: Biometry measurements in the cycloplegic stage should be considered in the IOL formulas that use parameters other than AL and K. Keywords: Haigis formula, intraocular lens, IOLMaster, optical biometry, pupillary dilation
format article
author Khambhiphant B
Sasiwilasagorn S
Chatbunchachai N
Pongpirul K
author_facet Khambhiphant B
Sasiwilasagorn S
Chatbunchachai N
Pongpirul K
author_sort Khambhiphant B
title Effect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry
title_short Effect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry
title_full Effect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry
title_fullStr Effect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry
title_full_unstemmed Effect of pupillary dilation on Haigis formula-calculated intraocular lens power measurement by using optical biometry
title_sort effect of pupillary dilation on haigis formula-calculated intraocular lens power measurement by using optical biometry
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/0a6ffedfcbf34a399f2c84da866267c4
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