Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain

YEATS domains are histone acylation readers that recognize crotonyllysine and acetyllysine. Here the authors provide structural insights into how YEATS domains recognize acetyllysines and further show that the human AF9 YEATS domain also binds DNA.

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Autores principales:	Brianna J. Klein, Kendra R. Vann, Forest H. Andrews, Wesley W. Wang, Jibo Zhang, Yi Zhang, Anastasia A. Beloglazkina, Wenyi Mi, Yuanyuan Li, Haitao Li, Xiaobing Shi, Andrei G. Kutateladze, Brian D. Strahl, Wenshe R. Liu, Tatiana G. Kutateladze
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0a782d5b6bf841aea5a1f2ccefd9b04c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:0a782d5b6bf841aea5a1f2ccefd9b04c2021-12-02T14:39:09ZStructural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain10.1038/s41467-018-07072-62041-1723https://doaj.org/article/0a782d5b6bf841aea5a1f2ccefd9b04c2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07072-6https://doaj.org/toc/2041-1723YEATS domains are histone acylation readers that recognize crotonyllysine and acetyllysine. Here the authors provide structural insights into how YEATS domains recognize acetyllysines and further show that the human AF9 YEATS domain also binds DNA.Brianna J. KleinKendra R. VannForest H. AndrewsWesley W. WangJibo ZhangYi ZhangAnastasia A. BeloglazkinaWenyi MiYuanyuan LiHaitao LiXiaobing ShiAndrei G. KutateladzeBrian D. StrahlWenshe R. LiuTatiana G. KutateladzeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Brianna J. Klein Kendra R. Vann Forest H. Andrews Wesley W. Wang Jibo Zhang Yi Zhang Anastasia A. Beloglazkina Wenyi Mi Yuanyuan Li Haitao Li Xiaobing Shi Andrei G. Kutateladze Brian D. Strahl Wenshe R. Liu Tatiana G. Kutateladze Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain
description	YEATS domains are histone acylation readers that recognize crotonyllysine and acetyllysine. Here the authors provide structural insights into how YEATS domains recognize acetyllysines and further show that the human AF9 YEATS domain also binds DNA.
format	article
author	Brianna J. Klein Kendra R. Vann Forest H. Andrews Wesley W. Wang Jibo Zhang Yi Zhang Anastasia A. Beloglazkina Wenyi Mi Yuanyuan Li Haitao Li Xiaobing Shi Andrei G. Kutateladze Brian D. Strahl Wenshe R. Liu Tatiana G. Kutateladze
author_facet	Brianna J. Klein Kendra R. Vann Forest H. Andrews Wesley W. Wang Jibo Zhang Yi Zhang Anastasia A. Beloglazkina Wenyi Mi Yuanyuan Li Haitao Li Xiaobing Shi Andrei G. Kutateladze Brian D. Strahl Wenshe R. Liu Tatiana G. Kutateladze
author_sort	Brianna J. Klein
title	Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain
title_short	Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain
title_full	Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain
title_fullStr	Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain
title_full_unstemmed	Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain
title_sort	structural insights into the π-π-π stacking mechanism and dna-binding activity of the yeats domain
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0a782d5b6bf841aea5a1f2ccefd9b04c
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Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain

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