Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

During cell division, the actin cytoskeletal network at both the equatorial contractile ring and cell cortex are known to play a role, but the regulation of γ-actin during cytokinesis is less well understood. Here, the authors show that recruitment of β-actin to the contractile ring and loss of γ-ac...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Anan Chen, Luisa Ulloa Severino, Thomas C. Panagiotou, Trevor F. Moraes, Darren A. Yuen, Brigitte D. Lavoie, Andrew Wilde
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0a7e937311fe4867849f9a4f60295ef9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0a7e937311fe4867849f9a4f60295ef9
record_format	dspace
spelling	oai:doaj.org-article:0a7e937311fe4867849f9a4f60295ef92021-12-02T13:39:22ZInhibition of polar actin assembly by astral microtubules is required for cytokinesis10.1038/s41467-021-22677-02041-1723https://doaj.org/article/0a7e937311fe4867849f9a4f60295ef92021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22677-0https://doaj.org/toc/2041-1723During cell division, the actin cytoskeletal network at both the equatorial contractile ring and cell cortex are known to play a role, but the regulation of γ-actin during cytokinesis is less well understood. Here, the authors show that recruitment of β-actin to the contractile ring and loss of γ-actin from the cell poles is required for completion of cell division.Anan ChenLuisa Ulloa SeverinoThomas C. PanagiotouTrevor F. MoraesDarren A. YuenBrigitte D. LavoieAndrew WildeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anan Chen Luisa Ulloa Severino Thomas C. Panagiotou Trevor F. Moraes Darren A. Yuen Brigitte D. Lavoie Andrew Wilde Inhibition of polar actin assembly by astral microtubules is required for cytokinesis
description	During cell division, the actin cytoskeletal network at both the equatorial contractile ring and cell cortex are known to play a role, but the regulation of γ-actin during cytokinesis is less well understood. Here, the authors show that recruitment of β-actin to the contractile ring and loss of γ-actin from the cell poles is required for completion of cell division.
format	article
author	Anan Chen Luisa Ulloa Severino Thomas C. Panagiotou Trevor F. Moraes Darren A. Yuen Brigitte D. Lavoie Andrew Wilde
author_facet	Anan Chen Luisa Ulloa Severino Thomas C. Panagiotou Trevor F. Moraes Darren A. Yuen Brigitte D. Lavoie Andrew Wilde
author_sort	Anan Chen
title	Inhibition of polar actin assembly by astral microtubules is required for cytokinesis
title_short	Inhibition of polar actin assembly by astral microtubules is required for cytokinesis
title_full	Inhibition of polar actin assembly by astral microtubules is required for cytokinesis
title_fullStr	Inhibition of polar actin assembly by astral microtubules is required for cytokinesis
title_full_unstemmed	Inhibition of polar actin assembly by astral microtubules is required for cytokinesis
title_sort	inhibition of polar actin assembly by astral microtubules is required for cytokinesis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0a7e937311fe4867849f9a4f60295ef9
work_keys_str_mv	AT ananchen inhibitionofpolaractinassemblybyastralmicrotubulesisrequiredforcytokinesis AT luisaulloaseverino inhibitionofpolaractinassemblybyastralmicrotubulesisrequiredforcytokinesis AT thomascpanagiotou inhibitionofpolaractinassemblybyastralmicrotubulesisrequiredforcytokinesis AT trevorfmoraes inhibitionofpolaractinassemblybyastralmicrotubulesisrequiredforcytokinesis AT darrenayuen inhibitionofpolaractinassemblybyastralmicrotubulesisrequiredforcytokinesis AT brigittedlavoie inhibitionofpolaractinassemblybyastralmicrotubulesisrequiredforcytokinesis AT andrewwilde inhibitionofpolaractinassemblybyastralmicrotubulesisrequiredforcytokinesis
_version_	1718392596693254144

Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

Ejemplares similares