Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.

Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.

<h4>Objectives</h4>Nucleoside reverse transcriptase inhibitors (NRTIs) used in HIV antiretroviral therapy can inhibit human telomerase reverse transcriptase. We therefore investigated whether in utero or childhood exposure to NRTIs affects leukocyte telomere length (LTL), a marker of cel...

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Autores principales: Hélène C F Côté, Hugo Soudeyns, Anona Thorne, Ariane Alimenti, Valérie Lamarre, Evelyn J Maan, Beheroze Sattha, Joel Singer, Normand Lapointe, Deborah M Money, John Forbes, CIHR Emerging Team in HIV therapy, aging (CARMA), Judy Wong, Ari Bitnun, Lindy Samson, Jason Brophy, David Burdge, Neora Pick, Julie van Schalkwyk, Julio Montaner, Marianne Harris, Patti Janssen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0a8923aa0732451c923996110afab929
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