A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors

Biological polymeric matrices often use molecular anchors, such as antibodies, to trap nanoparticulates. Here, the authors find that anchor-matrix bonds that are weak and short-lived confer superior trapping potency, contrary to the prevailing belief that effective molecular anchors should form stro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jay Newby, Jennifer L. Schiller, Timothy Wessler, Jasmine Edelstein, M. Gregory Forest, Samuel K. Lai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/0a8f61c054d7499c8cfd1b1294055ed1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Biological polymeric matrices often use molecular anchors, such as antibodies, to trap nanoparticulates. Here, the authors find that anchor-matrix bonds that are weak and short-lived confer superior trapping potency, contrary to the prevailing belief that effective molecular anchors should form strong bonds to both the matrix and the nanoparticulates.