Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome

Background: Spindle cell carcinoma (SpCC) is an unusual form of squamous cell carcinoma (SCC) and can sometimes present in the breast. Owing to the rarity of breast SpCC, few case studies are available nowadays and proper evidence is scarce. Case presentation: We herein report a 60-year-old fema...

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Autores principales:	Mohammad Naser Athamnah, Shatha M. Al-Barrak, Nimah A. Rabai, Tea Natelauri, Hussein S O Al Azzam, Mohammed Alorjani, Omar M. Al-Rusan, Amer Abu-Shanab
Formato:	article
Lenguaje:	EN
Publicado:	Kaviani Breast Disease Institute 2021
Materias:	Spindle cell carcinoma Breast cancer Jordan Breast pathology Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/0a900fc52ea241f38f2984fc436e0391
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spelling	oai:doaj.org-article:0a900fc52ea241f38f2984fc436e03912021-12-04T02:18:53ZSpindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome10.32768/abc.202184350-3572383-0433https://doaj.org/article/0a900fc52ea241f38f2984fc436e03912021-10-01T00:00:00Zhttps://www.archbreastcancer.com/index.php/abc/article/view/430https://doaj.org/toc/2383-0433 Background: Spindle cell carcinoma (SpCC) is an unusual form of squamous cell carcinoma (SCC) and can sometimes present in the breast. Owing to the rarity of breast SpCC, few case studies are available nowadays and proper evidence is scarce. Case presentation: We herein report a 60-year-old female patient, who was referred to the surgery services after presenting with a right breast ulcerated mass. On physical examination, a 7x7 cm mass was found along with a 3 cm ulcer on the top of it. Both mammography and ultrasound showed a dense mass, and tru-cut and skin punch biopsies confirmed neoplastic spindle cells within the lesion. The patient underwent a right total mastectomy with sentinel lymph node biopsies with no further chemotherapy or radiotherapy. Conclusion: Owing to the heterogeneity of SpCC, there is no exact treatment protocol for this type of cancer, and mastectomy or conservative surgery can be performed in certain groups of patients depending on tumor size, stage, and lymph node involvement. Fortunately, promising medical and biological therapies might be of use in the near future. Mohammad Naser AthamnahShatha M. Al-BarrakNimah A. RabaiTea NatelauriHussein S O Al AzzamMohammed AlorjaniOmar M. Al-RusanAmer Abu-ShanabKaviani Breast Disease InstitutearticleSpindle cell carcinomaBreast cancerJordanBreast pathologyNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENArchives of Breast Cancer (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Spindle cell carcinoma Breast cancer Jordan Breast pathology Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Spindle cell carcinoma Breast cancer Jordan Breast pathology Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Mohammad Naser Athamnah Shatha M. Al-Barrak Nimah A. Rabai Tea Natelauri Hussein S O Al Azzam Mohammed Alorjani Omar M. Al-Rusan Amer Abu-Shanab Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome
description	Background: Spindle cell carcinoma (SpCC) is an unusual form of squamous cell carcinoma (SCC) and can sometimes present in the breast. Owing to the rarity of breast SpCC, few case studies are available nowadays and proper evidence is scarce. Case presentation: We herein report a 60-year-old female patient, who was referred to the surgery services after presenting with a right breast ulcerated mass. On physical examination, a 7x7 cm mass was found along with a 3 cm ulcer on the top of it. Both mammography and ultrasound showed a dense mass, and tru-cut and skin punch biopsies confirmed neoplastic spindle cells within the lesion. The patient underwent a right total mastectomy with sentinel lymph node biopsies with no further chemotherapy or radiotherapy. Conclusion: Owing to the heterogeneity of SpCC, there is no exact treatment protocol for this type of cancer, and mastectomy or conservative surgery can be performed in certain groups of patients depending on tumor size, stage, and lymph node involvement. Fortunately, promising medical and biological therapies might be of use in the near future.
format	article
author	Mohammad Naser Athamnah Shatha M. Al-Barrak Nimah A. Rabai Tea Natelauri Hussein S O Al Azzam Mohammed Alorjani Omar M. Al-Rusan Amer Abu-Shanab
author_facet	Mohammad Naser Athamnah Shatha M. Al-Barrak Nimah A. Rabai Tea Natelauri Hussein S O Al Azzam Mohammed Alorjani Omar M. Al-Rusan Amer Abu-Shanab
author_sort	Mohammad Naser Athamnah
title	Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome
title_short	Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome
title_full	Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome
title_fullStr	Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome
title_full_unstemmed	Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome
title_sort	spindle cell carcinoma of the breast: a case report representing diagnostics, therapeutics, intervention, and outcome
publisher	Kaviani Breast Disease Institute
publishDate	2021
url	https://doaj.org/article/0a900fc52ea241f38f2984fc436e0391
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Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome

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