Amyloid precursor protein is trafficked and secreted via synaptic vesicles.

Amyloid precursor protein is trafficked and secreted via synaptic vesicles.

A large body of evidence has implicated amyloid precursor protein (APP) and its proteolytic derivatives as key players in the physiological context of neuronal synaptogenesis and synapse maintenance, as well as in the pathology of Alzheimer's Disease (AD). Although APP processing and release ar...

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Autores principales: Teja W Groemer, Cora S Thiel, Matthew Holt, Dietmar Riedel, Yunfeng Hua, Jana Hüve, Benjamin G Wilhelm, Jürgen Klingauf
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/0a96d424466346ceb490fa796332a47d
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