Dissecting the contribution of O-Antigen and proteins to the immunogenicity of Shigella sonnei generalized modules for membrane antigens (GMMA)

Dissecting the contribution of O-Antigen and proteins to the immunogenicity of Shigella sonnei generalized modules for membrane antigens (GMMA)

Abstract GMMA are exosomes released from engineered Gram-negative bacteria resembling the composition of outer membranes. We applied the GMMA technology for the development of an O-Antigen (OAg) based vaccine against Shigella sonnei, the most epidemiologically relevant cause of shigellosis. S. sonne...

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Autores principales: Francesca Mancini, Gianmarco Gasperini, Omar Rossi, Maria Grazia Aruta, Maria Michelina Raso, Renzo Alfini, Massimiliano Biagini, Francesca Necchi, Francesca Micoli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0a9858c796534422bc600eb1b85c85dd
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