Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach
Aria Khademi,1–3 Yasser EL-Manzalawy,1,4 Lindsay Master,5 Orfeu M Buxton,5–9 Vasant G Honavar1–3,6,10,11 1College of Information Sciences and Technology, The Pennsylvania State University, University Park, PA, USA; 2Artificial Intelligence Research Laboratory, The Penns...
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Dove Medical Press
2019
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actigraphy polysomnography personalized machine learning sleep parameters Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495 |
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actigraphy polysomnography personalized machine learning sleep parameters Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495 Khademi A EL-Manzalawy Y Master L Buxton OM Honavar VG Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach |
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Aria Khademi,1–3 Yasser EL-Manzalawy,1,4 Lindsay Master,5 Orfeu M Buxton,5–9 Vasant G Honavar1–3,6,10,11 1College of Information Sciences and Technology, The Pennsylvania State University, University Park, PA, USA; 2Artificial Intelligence Research Laboratory, The Pennsylvania State University, University Park, PA, USA; 3Center for Big Data Analytics and Discovery Informatics, The Pennsylvania State University, University Park, PA, USA; 4Department of Imaging Science and Innovation, Geisinger Health System, Danville, PA, 17822, USA; 5Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA, USA; 6Clinical and Translational Sciences Institute, The Pennsylvania State University, University Park, PA, USA; 7Division of Sleep Medicine, Harvard University, Boston, MA, USA; 8Department of Social and Behavioral Sciences, Harvard Chan School of Public Health, Boston, MA, USA; 9Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women’s Hospital, Boston, MA, USA; 10Institute for Computational and Data Sciences, The Pennsylvania State University, University Park, PA, USA; 11Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USACorrespondence: Orfeu M BuxtonThe Pennsylvania State University, University Park, PA 16802, USATel +1 814 865 3141Email orfeu@psu.eduBackground: The current gold standard for measuring sleep is polysomnography (PSG), but it can be obtrusive and costly. Actigraphy is a relatively low-cost and unobtrusive alternative to PSG. Of particular interest in measuring sleep from actigraphy is prediction of sleep-wake states. Current literature on prediction of sleep-wake states from actigraphy consists of methods that use population data, which we call generalized models. However, accounting for variability of sleep patterns across individuals calls for personalized models of sleep-wake states prediction that could be potentially better suited to individual-level data and yield more accurate estimation of sleep.Purpose: To investigate the validity of developing personalized machine learning models, trained and tested on individual-level actigraphy data, for improved prediction of sleep-wake states and reliable estimation of nightly sleep parameters.Participants and methods: We used a dataset including 54 participants and systematically trained and tested 5 different personalized machine learning models as well as their generalized counterparts. We evaluated model performance compared to concurrent PSG through extensive machine learning experiments and statistical analyses.Results: Our experiments show the superiority of personalized models over their generalized counterparts in estimating PSG-derived sleep parameters. Personalized models of regularized logistic regression, random forest, adaptive boosting, and extreme gradient boosting achieve estimates of total sleep time, wake after sleep onset, sleep efficiency, and number of awakenings that are closer to those obtained by PSG, in absolute difference, than the same estimates from their generalized counterparts. We further show that the difference between estimates of sleep parameters obtained by personalized models and those of PSG is statistically non-significant.Conclusion: Personalized machine learning models of sleep-wake states outperform their generalized counterparts in terms of estimating sleep parameters and are indistinguishable from PSG labeled sleep-wake states. Personalized machine learning models can be used in actigraphy studies of sleep health and potentially screening for some sleep disorders.Keywords: actigraphy, polysomnography, personalized, machine learning, sleep parameters |
| format |
article |
| author |
Khademi A EL-Manzalawy Y Master L Buxton OM Honavar VG |
| author_facet |
Khademi A EL-Manzalawy Y Master L Buxton OM Honavar VG |
| author_sort |
Khademi A |
| title |
Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach |
| title_short |
Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach |
| title_full |
Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach |
| title_fullStr |
Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach |
| title_full_unstemmed |
Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach |
| title_sort |
personalized sleep parameters estimation from actigraphy: a machine learning approach |
| publisher |
Dove Medical Press |
| publishDate |
2019 |
| url |
https://doaj.org/article/0a9fdc6c6b5e473db580ad3dc6c74aaf |
| work_keys_str_mv |
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1718401712071376896 |
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oai:doaj.org-article:0a9fdc6c6b5e473db580ad3dc6c74aaf2021-12-02T03:25:57ZPersonalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach1179-1608https://doaj.org/article/0a9fdc6c6b5e473db580ad3dc6c74aaf2019-12-01T00:00:00Zhttps://www.dovepress.com/personalized-sleep-parameters-estimation-from-actigraphy-a-machine-lea-peer-reviewed-article-NSShttps://doaj.org/toc/1179-1608Aria Khademi,1–3 Yasser EL-Manzalawy,1,4 Lindsay Master,5 Orfeu M Buxton,5–9 Vasant G Honavar1–3,6,10,11 1College of Information Sciences and Technology, The Pennsylvania State University, University Park, PA, USA; 2Artificial Intelligence Research Laboratory, The Pennsylvania State University, University Park, PA, USA; 3Center for Big Data Analytics and Discovery Informatics, The Pennsylvania State University, University Park, PA, USA; 4Department of Imaging Science and Innovation, Geisinger Health System, Danville, PA, 17822, USA; 5Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA, USA; 6Clinical and Translational Sciences Institute, The Pennsylvania State University, University Park, PA, USA; 7Division of Sleep Medicine, Harvard University, Boston, MA, USA; 8Department of Social and Behavioral Sciences, Harvard Chan School of Public Health, Boston, MA, USA; 9Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women’s Hospital, Boston, MA, USA; 10Institute for Computational and Data Sciences, The Pennsylvania State University, University Park, PA, USA; 11Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USACorrespondence: Orfeu M BuxtonThe Pennsylvania State University, University Park, PA 16802, USATel +1 814 865 3141Email orfeu@psu.eduBackground: The current gold standard for measuring sleep is polysomnography (PSG), but it can be obtrusive and costly. Actigraphy is a relatively low-cost and unobtrusive alternative to PSG. Of particular interest in measuring sleep from actigraphy is prediction of sleep-wake states. Current literature on prediction of sleep-wake states from actigraphy consists of methods that use population data, which we call generalized models. However, accounting for variability of sleep patterns across individuals calls for personalized models of sleep-wake states prediction that could be potentially better suited to individual-level data and yield more accurate estimation of sleep.Purpose: To investigate the validity of developing personalized machine learning models, trained and tested on individual-level actigraphy data, for improved prediction of sleep-wake states and reliable estimation of nightly sleep parameters.Participants and methods: We used a dataset including 54 participants and systematically trained and tested 5 different personalized machine learning models as well as their generalized counterparts. We evaluated model performance compared to concurrent PSG through extensive machine learning experiments and statistical analyses.Results: Our experiments show the superiority of personalized models over their generalized counterparts in estimating PSG-derived sleep parameters. Personalized models of regularized logistic regression, random forest, adaptive boosting, and extreme gradient boosting achieve estimates of total sleep time, wake after sleep onset, sleep efficiency, and number of awakenings that are closer to those obtained by PSG, in absolute difference, than the same estimates from their generalized counterparts. We further show that the difference between estimates of sleep parameters obtained by personalized models and those of PSG is statistically non-significant.Conclusion: Personalized machine learning models of sleep-wake states outperform their generalized counterparts in terms of estimating sleep parameters and are indistinguishable from PSG labeled sleep-wake states. Personalized machine learning models can be used in actigraphy studies of sleep health and potentially screening for some sleep disorders.Keywords: actigraphy, polysomnography, personalized, machine learning, sleep parametersKhademi AEL-Manzalawy YMaster LBuxton OMHonavar VGDove Medical Pressarticleactigraphypolysomnographypersonalizedmachine learningsleep parametersPsychiatryRC435-571Neurophysiology and neuropsychologyQP351-495ENNature and Science of Sleep, Vol Volume 11, Pp 387-399 (2019) |